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Aberrant immune regulation and enrichment of stem-like CD8+ T cells in the pancreatic lymph node during type 1 diabetes development.

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Title: Aberrant immune regulation and enrichment of stem-like CD8+ T cells in the pancreatic lymph node during type 1 diabetes development.
Authors: Peters LD; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA., Seay HR; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA., Smith J; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA., Posgai AL; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA., Berkowitz R; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA., Wasserfall CH; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA., Atkinson MA; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, USA., Bacher R; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Biostatistics, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., Brusko MA; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA., Brusko TM; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 01. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Aberrant immune regulation and enrichment of stem-like CD8<superscript>+</superscript> T cells in the pancreatic lymph node during type 1 diabetes development.
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  Data: <searchLink fieldCode="AU" term="%22Peters+LD%22">Peters LD</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Seay+HR%22">Seay HR</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Smith+J%22">Smith J</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Posgai+AL%22">Posgai AL</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Berkowitz+R%22">Berkowitz R</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wasserfall+CH%22">Wasserfall CH</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Atkinson+MA%22">Atkinson MA</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Bacher+R%22">Bacher R</searchLink>; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Biostatistics, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Brusko+MA%22">Brusko MA</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Brusko+TM%22">Brusko TM</searchLink>; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA.
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              Text: 2026 Apr 01
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