CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4c.

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Title: CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4c.
Authors: Burton EM; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America., Liao Y; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America., Maestri D; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America., Mitra B; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America., Gewurz BE; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 01. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2026.03.31.715635