CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4c.
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| Title: | CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4c. |
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| Authors: | Burton EM; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America., Liao Y; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America., Maestri D; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America., Mitra B; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America., Gewurz BE; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 01. Date of Electronic Publication: 2026 Apr 01. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41959378 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4c. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Burton+EM%22">Burton EM</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Liao+Y%22">Liao Y</searchLink>; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Maestri+D%22">Maestri D</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Mitra+B%22">Mitra B</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Gewurz+BE%22">Gewurz BE</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts, United States of America.; Center for Integrated Solutions for Infectious Diseases, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, United States of America.; Program in Virology, Harvard Medical School, Boston, Massachusetts, United States of America. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Apr 01. <i>Date of Electronic Publication: </i>2026 Apr 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41959378 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.64898/2026.03.31.715635 Languages: – Code: eng Text: English Titles: – TitleFull: CRISPR Screens Reveal Epstein-Barr Virus-activated JunB as a Key Lymphoblastoid B cell Dependency Factor that Represses Cyclin Dependent Kinase Inhibitor P18INK4c. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Burton EM – PersonEntity: Name: NameFull: Liao Y – PersonEntity: Name: NameFull: Maestri D – PersonEntity: Name: NameFull: Mitra B – PersonEntity: Name: NameFull: Gewurz BE IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2026 Apr 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2692-8205 Titles: – TitleFull: BioRxiv : the preprint server for biology Type: main |
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