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FMR1 reduction alters cellular and circuit properties in human cortex.

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Title: FMR1 reduction alters cellular and circuit properties in human cortex.
Authors: Singh A; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Abbaspoor S; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Chung L; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Heinrich MJ; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Stone S; Department of Neurosurgery, Harvard Medical School, Boston, MA, USA., Lidov H; Department of Pathology, Harvard Medical School, Boston, MA, USA., Maio B; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Phuoc-Tran T; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Yoon J; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Teng J; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Martinez-Reyes C; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Hammarlund E; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Xu X; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Rotenberg A; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Gavornik J; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Ferguson B; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA., Farrell JS; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA., Osterweil EK; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 12. Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 41959475
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PubType: Academic Journal
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  Data: FMR1 reduction alters cellular and circuit properties in human cortex.
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  Data: <searchLink fieldCode="AU" term="%22Singh+A%22">Singh A</searchLink>; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Abbaspoor+S%22">Abbaspoor S</searchLink>; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chung+L%22">Chung L</searchLink>; Hansjoerg Wyss and Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, MA, USA.; F. M. 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        Value: 10.64898/2026.03.11.711123
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