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Preinfusion risk factors for the development of severe neurotoxicity following CART therapy in pediatric patients.

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Title: Preinfusion risk factors for the development of severe neurotoxicity following CART therapy in pediatric patients.
Authors: Diorio C; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Myers RM; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Li Y; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States., Liu H; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Belfer S; Division of Neurology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Neurology Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., DiNofia A; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Leahy AB; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Newman H; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Dolan J; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States., Martinez Z; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States., Elhachimi A; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States., Lindell RB; Division of Critical Care Medicine at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Anesthesiology and Critical Care Medicine Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Mullen C; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States., Li A; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States., Kim J; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States., Teachey DT; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Maude SL; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., Grupp SA; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States., McGuire JL; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.; Division of Neurology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Neurology Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.
Source: HemaSphere [Hemasphere] 2026 Apr 08; Vol. 10 (4), pp. e70337. Date of Electronic Publication: 2026 Apr 08 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Diorio+C%22">Diorio C</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Myers+RM%22">Myers RM</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Belfer+S%22">Belfer S</searchLink>; Division of Neurology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Neurology Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22DiNofia+A%22">DiNofia A</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Leahy+AB%22">Leahy AB</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Newman+H%22">Newman H</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; 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Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Li+A%22">Li A</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Teachey+DT%22">Teachey DT</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Maude+SL%22">Maude SL</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22Grupp+SA%22">Grupp SA</searchLink>; Division of Oncology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.<br /><searchLink fieldCode="AU" term="%22McGuire+JL%22">McGuire JL</searchLink>; Department of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.; Division of Neurology at the Children's Hospital of Philadelphia Philadelphia Pennsylvania United States.; Department of Neurology Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania United States.
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  Data: <searchLink fieldCode="JN" term="%22101740619%22">HemaSphere</searchLink> [Hemasphere] 2026 Apr 08; Vol. 10 (4), pp. e70337. <i>Date of Electronic Publication: </i>2026 Apr 08 (<i>Print Publication: </i>2026).
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