Protective effect of nebivolol on bleomycin-induced lung fibrosis via suppressing TLR4/IL-1β/MMP-2 and TGF-β/HSP47 signaling pathways in rats.

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Title: Protective effect of nebivolol on bleomycin-induced lung fibrosis via suppressing TLR4/IL-1β/MMP-2 and TGF-β/HSP47 signaling pathways in rats.
Authors: Morsy MA; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Abdel-Gaber SA; Department of Medical Pharmacology, Faculty of Medicine, Minia University, El-Minia, Egypt., Abed El Baky MF; Department of Medical Biochemistry, Faculty of Medicine, Minia University, El-Minia, Egypt., Abdel Hafez SMN; Department of Histology and Cell Biology, Faculty of Medicine, Minia University, El-Minia, Egypt., Nair AB; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Venugopala KN; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Shinu P; Department of Biomedical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia., Ibrahim YF; Department of Medical Pharmacology, Faculty of Medicine, Minia University, El-Minia, Egypt.
Source: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2026 Jun; Vol. 48 (3), pp. 375-387. Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8800150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2513 (Electronic) Linking ISSN: 08923973 NLM ISO Abbreviation: Immunopharmacol Immunotoxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Protective effect of nebivolol on bleomycin-induced lung fibrosis via suppressing TLR4/IL-1β/MMP-2 and TGF-β/HSP47 signaling pathways in rats.
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  Data: <searchLink fieldCode="AU" term="%22Morsy+MA%22">Morsy MA</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Abdel-Gaber+SA%22">Abdel-Gaber SA</searchLink>; Department of Medical Pharmacology, Faculty of Medicine, Minia University, El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Abed+El+Baky+MF%22">Abed El Baky MF</searchLink>; Department of Medical Biochemistry, Faculty of Medicine, Minia University, El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdel+Hafez+SMN%22">Abdel Hafez SMN</searchLink>; Department of Histology and Cell Biology, Faculty of Medicine, Minia University, El-Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Nair+AB%22">Nair AB</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Venugopala+KN%22">Venugopala KN</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Shinu+P%22">Shinu P</searchLink>; Department of Biomedical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ibrahim+YF%22">Ibrahim YF</searchLink>; Department of Medical Pharmacology, Faculty of Medicine, Minia University, El-Minia, Egypt.
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  Data: <searchLink fieldCode="JN" term="%228800150%22">Immunopharmacology and immunotoxicology</searchLink> [Immunopharmacol Immunotoxicol] 2026 Jun; Vol. 48 (3), pp. 375-387. <i>Date of Electronic Publication: </i>2026 Apr 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8800150 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-2513 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208923973%22">08923973 </searchLink><i>NLM ISO Abbreviation: </i>Immunopharmacol Immunotoxicol <i>Subsets: </i>MEDLINE
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        Value: 10.1080/08923973.2026.2655392
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        Text: English
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        StartPage: 375
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      – TitleFull: Protective effect of nebivolol on bleomycin-induced lung fibrosis via suppressing TLR4/IL-1β/MMP-2 and TGF-β/HSP47 signaling pathways in rats.
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              Text: 2026 Jun
              Type: published
              Y: 2026
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