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Hexokinase 3 promoted cytokine production of monocytes by targeting metabolic reprogramming and histone lactylation in sepsis.

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Title: Hexokinase 3 promoted cytokine production of monocytes by targeting metabolic reprogramming and histone lactylation in sepsis.
Authors: Lian C; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China., Xu Q; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China., Shi H; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China., Xie Y; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China., Fang J; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China., Rao B; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China., Ji T; State Key Laboratory of Respiratory Disease, Clinical Laboratory Medicine Department, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, People's Republic of China., Jiang H; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China., Wu Z; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China. 21490416@qq.com., Chen XH; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China. cxhgz168paper@163.com., Lin SP; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China. linsp@qq.com.
Source: Clinical epigenetics [Clin Epigenetics] 2026 Apr 10; Vol. 18 (1). Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083 (Electronic) Linking ISSN: 18687075 NLM ISO Abbreviation: Clin Epigenetics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hexokinase 3 promoted cytokine production of monocytes by targeting metabolic reprogramming and histone lactylation in sepsis.
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  Data: <searchLink fieldCode="AU" term="%22Lian+C%22">Lian C</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Shi+H%22">Shi H</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xie+Y%22">Xie Y</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Fang+J%22">Fang J</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Rao+B%22">Rao B</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ji+T%22">Ji T</searchLink>; State Key Laboratory of Respiratory Disease, Clinical Laboratory Medicine Department, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wu+Z%22">Wu Z</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China. 21490416@qq.com.<br /><searchLink fieldCode="AU" term="%22Chen+XH%22">Chen XH</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China. cxhgz168paper@163.com.<br /><searchLink fieldCode="AU" term="%22Lin+SP%22">Lin SP</searchLink>; Department of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510260, People's Republic of China. linsp@qq.com.
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  Data: <searchLink fieldCode="JN" term="%22101516977%22">Clinical epigenetics</searchLink> [Clin Epigenetics] 2026 Apr 10; Vol. 18 (1). <i>Date of Electronic Publication: </i>2026 Apr 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Biomed+Central%22">Biomed Central </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101516977 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1868-7083 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218687075%22">18687075 </searchLink><i>NLM ISO Abbreviation: </i>Clin Epigenetics <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41964014
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        Value: 10.1186/s13148-026-02129-6
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        Text: English
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      – TitleFull: Hexokinase 3 promoted cytokine production of monocytes by targeting metabolic reprogramming and histone lactylation in sepsis.
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            – D: 10
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              Text: 2026 Apr 10
              Type: published
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