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Nintedanib in progressive bronchiolitis obliterans syndrome (BOS) grade 0p-1-2 in lung transplant recipients (INFINITIx-BOS): protocol of a French multicenter randomized controlled trial.

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Title: Nintedanib in progressive bronchiolitis obliterans syndrome (BOS) grade 0p-1-2 in lung transplant recipients (INFINITIx-BOS): protocol of a French multicenter randomized controlled trial.
Authors: Brugière O; Service de Pneumologie Et Transplantation Pulmonaire, Hôpital Foch, Suresnes, France. o.brugiere@hopital-foch.com.; U976 HIPI, IRSL, Université Paris Cité, Paris, France. o.brugiere@hopital-foch.com., Hirschi S; Department of Pneumology, Strasbourg Lung Transplant Program, Strasbourg University Hospital, Strasbourg, France., Reynaud-Gaubert M; Service de Pneumologie Et Transplantation Pulmonaire, CHU de Marseille, Marseille, France., Bunel V; APHP.Nord-Université de Paris, Hôpital Bichat-Claude Bernard, Service de Pneumologie B Et Transplantation Pulmonaire, Paris, France., Demant X; Service de Pneumologie Et Transplantation Pulmonaire, CHU de Bordeaux, Bordeaux, France., Le Pavec J; Service de Pneumologie Et Transplantation Pulmonaire, Hôpital Marie-Lannelongue, Le Plessis-Robinson, France., Falque L; Service Hospitalier Universitaire de Pneumologie Et Physiologie, Pôle Thorax Et Vaisseaux, CHU Grenoble Alpes, Grenoble, France., Si Mohammed N; Unité de Recherche Clinique Paris Nord Val de Seine, URC PNVS, Hôpital Bichat, Paris, France., Tardivon C; Unité de Recherche Clinique Paris Nord Val de Seine, URC PNVS, Hôpital Bichat, Paris, France., Couffignal C; Unité de Recherche Clinique Paris Nord Val de Seine, URC PNVS, Hôpital Bichat, Paris, France.
Corporate Authors: INFINITIx-BOS Consortium
Source: Trials [Trials] 2026 Apr 11; Vol. 27 (1). Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Nintedanib in progressive bronchiolitis obliterans syndrome (BOS) grade 0p-1-2 in lung transplant recipients (INFINITIx-BOS): protocol of a French multicenter randomized controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Brugière+O%22">Brugière O</searchLink>; Service de Pneumologie Et Transplantation Pulmonaire, Hôpital Foch, Suresnes, France. o.brugiere@hopital-foch.com.; U976 HIPI, IRSL, Université Paris Cité, Paris, France. o.brugiere@hopital-foch.com.<br /><searchLink fieldCode="AU" term="%22Hirschi+S%22">Hirschi S</searchLink>; Department of Pneumology, Strasbourg Lung Transplant Program, Strasbourg University Hospital, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Reynaud-Gaubert+M%22">Reynaud-Gaubert M</searchLink>; Service de Pneumologie Et Transplantation Pulmonaire, CHU de Marseille, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Bunel+V%22">Bunel V</searchLink>; APHP.Nord-Université de Paris, Hôpital Bichat-Claude Bernard, Service de Pneumologie B Et Transplantation Pulmonaire, Paris, France.<br /><searchLink fieldCode="AU" term="%22Demant+X%22">Demant X</searchLink>; Service de Pneumologie Et Transplantation Pulmonaire, CHU de Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Le+Pavec+J%22">Le Pavec J</searchLink>; Service de Pneumologie Et Transplantation Pulmonaire, Hôpital Marie-Lannelongue, Le Plessis-Robinson, France.<br /><searchLink fieldCode="AU" term="%22Falque+L%22">Falque L</searchLink>; Service Hospitalier Universitaire de Pneumologie Et Physiologie, Pôle Thorax Et Vaisseaux, CHU Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Si+Mohammed+N%22">Si Mohammed N</searchLink>; Unité de Recherche Clinique Paris Nord Val de Seine, URC PNVS, Hôpital Bichat, Paris, France.<br /><searchLink fieldCode="AU" term="%22Tardivon+C%22">Tardivon C</searchLink>; Unité de Recherche Clinique Paris Nord Val de Seine, URC PNVS, Hôpital Bichat, Paris, France.<br /><searchLink fieldCode="AU" term="%22Couffignal+C%22">Couffignal C</searchLink>; Unité de Recherche Clinique Paris Nord Val de Seine, URC PNVS, Hôpital Bichat, Paris, France.
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  Data: <searchLink fieldCode="CA" term="%22INFINITIx-BOS+Consortium%22">INFINITIx-BOS Consortium</searchLink>
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              Text: 2026 Apr 11
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