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Sex- and age-dependent mitochondrial dysfunction and cognitive impairment in a mouse model of familial hypercholesterolemia.

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Title: Sex- and age-dependent mitochondrial dysfunction and cognitive impairment in a mouse model of familial hypercholesterolemia.
Authors: Prado-Lopes N; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil., Fagundes D; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil., Tavares L; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil., Santos W; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil., Barros W; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil., Moschen H; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil., Mortari M; Laboratory of Neuropharmacology, Department of Physiological Sciences, Biology Institute, University of Brasilia, Brasília, DF, Brazil., Goulart J; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil., Amato A; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil., de Oliveira J; Department of Biochemistry, Graduate Program in Biological Sciences: Biochemistry, Institute of Basic Health Sciences (ICBS), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil., Bellozi P; Laboratory of Molecular Pharmacology, Department of Pharmacy, Faculty of Health Sciences, University of Brasília, Brasília, DF, Brazil., de Bem AF; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil. debemandreza@gmail.com.; Brazilian National Institute of Science and Technology on Neuroimmunomodulation, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil. debemandreza@gmail.com.
Source: Biology of sex differences [Biol Sex Differ] 2026 Apr 10; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101548963 Publication Model: Electronic Cited Medium: Internet ISSN: 2042-6410 (Electronic) Linking ISSN: 20426410 NLM ISO Abbreviation: Biol Sex Differ Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sex- and age-dependent mitochondrial dysfunction and cognitive impairment in a mouse model of familial hypercholesterolemia.
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  Data: <searchLink fieldCode="AU" term="%22Prado-Lopes+N%22">Prado-Lopes N</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22Fagundes+D%22">Fagundes D</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22Tavares+L%22">Tavares L</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22Santos+W%22">Santos W</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22Barros+W%22">Barros W</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22Moschen+H%22">Moschen H</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22Mortari+M%22">Mortari M</searchLink>; Laboratory of Neuropharmacology, Department of Physiological Sciences, Biology Institute, University of Brasilia, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22Goulart+J%22">Goulart J</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22Amato+A%22">Amato A</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+J%22">de Oliveira J</searchLink>; Department of Biochemistry, Graduate Program in Biological Sciences: Biochemistry, Institute of Basic Health Sciences (ICBS), Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Bellozi+P%22">Bellozi P</searchLink>; Laboratory of Molecular Pharmacology, Department of Pharmacy, Faculty of Health Sciences, University of Brasília, Brasília, DF, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Bem+AF%22">de Bem AF</searchLink>; Laboratory of Bioenergetics and Metabolism, Department of Genetics and Morphology, Institute of Biology, University of Brasília, Brasília, DF, Brazil. debemandreza@gmail.com.; Brazilian National Institute of Science and Technology on Neuroimmunomodulation, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil. debemandreza@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101548963%22">Biology of sex differences</searchLink> [Biol Sex Differ] 2026 Apr 10; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101548963 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2042-6410 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220426410%22">20426410 </searchLink><i>NLM ISO Abbreviation: </i>Biol Sex Differ <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 10
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