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The association between APOE 𝜀4 carrierships and the detection of amyloid positivity using an Alzheimer's disease proteomic blood test in asymptomatic Down syndrome.

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Title: The association between APOE 𝜀4 carrierships and the detection of amyloid positivity using an Alzheimer's disease proteomic blood test in asymptomatic Down syndrome.
Authors: Abdullah LB; Department of Family Medicine, UNT Health Fort Worth, Fort Worth, Texas, USA., Zhang F; Department of Family Medicine, UNT Health Fort Worth, Fort Worth, Texas, USA., Petersen M; Department of Family Medicine, UNT Health Fort Worth, Fort Worth, Texas, USA., Hall J; Department of Family Medicine, UNT Health Fort Worth, Fort Worth, Texas, USA., Handen BL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Mapstone M; Department of Neurology, University of California, Irvine, California, USA., Christian B; Department of Pediatrics, University of California, Irvine, School of Medicine, Orange, California, USA., Head E; Department of Pediatrics, University of California, Irvine, School of Medicine, Orange, California, USA., Harley S; University of Wisconsin Madison, Waisman Center, Madison, Wisconsin, USA., Andrews H; Department of Neurology New York, Columbia University, Vagelos College of Physicians and Surgeons, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, New York, USA., Lee JH; Department of Neurology New York, Columbia University, Vagelos College of Physicians and Surgeons, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, New York, New York, USA., Tudorascu D; Department of Pediatrics, University of California, Irvine, School of Medicine, Orange, California, USA., Hom C; Department of Psychiatry and Human Behavior, University of California, Irvine (UCI) School of Medicine, Orange, California, USA., Zaman S; Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Brickman AM; Department of Psychiatry and Human Behavior, University of California, Irvine (UCI) School of Medicine, Orange, California, USA., Rosas D; Departments of Neurology and Radiology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, USA., Cohen A; Department of Pediatrics, University of California, Irvine, School of Medicine, Orange, California, USA., Harp JP; Kentucky Neuroscience Institute & Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, Kentucky, USA., Schmitt F; Department of Pediatrics, University of California, Irvine, School of Medicine, Orange, California, USA., Ptomey L; University of Kansas Medical Center, Kansas City, Kansas, USA., Burns JM; Department of Radiology, Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Lott IT; Department of Pediatrics, University of California, Irvine, School of Medicine, Orange, California, USA., Lai F; Department of Pathology, University of California, Irvine, Irvine, California, USA., Laymon C; Department of Radiology, Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Cruchaga C; Department of Psychiatry, Washington University in St. Louis, St. Louis, Missouri, USA., O'Bryant S; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ances BM; Department of Pathology, University of California, Irvine, Irvine, California, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Apr; Vol. 22 (4), pp. e71338.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The association between APOE 𝜀4 carrierships and the detection of amyloid positivity using an Alzheimer's disease proteomic blood test in asymptomatic Down syndrome.
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