Novel pleiotropic loci link vascular and immune pathways in systemic sclerosis and primary Raynaud's phenomenon.

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Title: Novel pleiotropic loci link vascular and immune pathways in systemic sclerosis and primary Raynaud's phenomenon.
Authors: Rangel-Peláez C; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain., Rodriguez-Martin I; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain., Rosa-Baez C; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain., Kerick M; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain., Guillén-Del-Castillo A; Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Simeón-Aznar CP; Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Barcelona, Spain., Callejas JL; Systemic Autoimmune Disease Unit, Hospital Clínico San Cecilio, Instituto de Investigación Biosanitaria Ibs.GRANADA, Granada, Spain., Distler O; Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Proudman SM; Rheumatology Unit, Royal Adelaide Hospital and the University of Adelaide, Adelaide, South Australia, Australia., Nikpour M; Department of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.; Faculty of Medicine and Health, The University of Sydney School of Public Health, Sydney, New South Wales, Australia., Hunzelmann N; Department of Dermatology and Venereology, University Hospital Cologne, Cologne, Germany., Moroncini G; Department of Clinical and Molecular Science, Marche Polytechnic University, Ancona, Italy.; Department of Internal Medicine, Marche University Hospital, Ancona, Italy., de Vries-Bouwstra JK; The Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands., Herrick AL; Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Allanore Y; Department of Rheumatology, Université Paris Cité UFR de Médecine, Paris, France., Alarcón-Riquelme ME; Centre for Genomics and Oncological Research, Pfizer, University of Granada/Andalusian Regional Government, Spain, Granada., Beretta L; Scleroderma Unit, Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy., Mayes MD; UT Health Houston, Division of Rheumatology, McGovern Medical School, Houston, TX, USA., Denton CP; Centre for Rheumatology, Royal Free Hospital, UCL, London, UK., Assassi S; UT Health Houston, Division of Rheumatology, McGovern Medical School, Houston, TX, USA., Martín J; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain., Acosta-Herrera M; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain., Ortiz-Fernández L; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.
Corporate Authors: and the International SSc Group, the PRECISESADS Clinical Consortium, and the Australian Scleroderma Interest Group (ASIG)#
Source: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2026 May 05; Vol. 65 (5).
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel pleiotropic loci link vascular and immune pathways in systemic sclerosis and primary Raynaud's phenomenon.
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  Data: <searchLink fieldCode="AU" term="%22Rangel-Peláez+C%22">Rangel-Peláez C</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Martin+I%22">Rodriguez-Martin I</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Rosa-Baez+C%22">Rosa-Baez C</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Kerick+M%22">Kerick M</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Guillén-Del-Castillo+A%22">Guillén-Del-Castillo A</searchLink>; Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Simeón-Aznar+CP%22">Simeón-Aznar CP</searchLink>; Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Callejas+JL%22">Callejas JL</searchLink>; Systemic Autoimmune Disease Unit, Hospital Clínico San Cecilio, Instituto de Investigación Biosanitaria Ibs.GRANADA, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Distler+O%22">Distler O</searchLink>; Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Proudman+SM%22">Proudman SM</searchLink>; Rheumatology Unit, Royal Adelaide Hospital and the University of Adelaide, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Nikpour+M%22">Nikpour M</searchLink>; Department of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.; Faculty of Medicine and Health, The University of Sydney School of Public Health, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Hunzelmann+N%22">Hunzelmann N</searchLink>; Department of Dermatology and Venereology, University Hospital Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Moroncini+G%22">Moroncini G</searchLink>; Department of Clinical and Molecular Science, Marche Polytechnic University, Ancona, Italy.; Department of Internal Medicine, Marche University Hospital, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22de+Vries-Bouwstra+JK%22">de Vries-Bouwstra JK</searchLink>; The Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Herrick+AL%22">Herrick AL</searchLink>; Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Allanore+Y%22">Allanore Y</searchLink>; Department of Rheumatology, Université Paris Cité UFR de Médecine, Paris, France.<br /><searchLink fieldCode="AU" term="%22Alarcón-Riquelme+ME%22">Alarcón-Riquelme ME</searchLink>; Centre for Genomics and Oncological Research, Pfizer, University of Granada/Andalusian Regional Government, Spain, Granada.<br /><searchLink fieldCode="AU" term="%22Beretta+L%22">Beretta L</searchLink>; Scleroderma Unit, Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mayes+MD%22">Mayes MD</searchLink>; UT Health Houston, Division of Rheumatology, McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Denton+CP%22">Denton CP</searchLink>; Centre for Rheumatology, Royal Free Hospital, UCL, London, UK.<br /><searchLink fieldCode="AU" term="%22Assassi+S%22">Assassi S</searchLink>; UT Health Houston, Division of Rheumatology, McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Martín+J%22">Martín J</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Acosta-Herrera+M%22">Acosta-Herrera M</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Ortiz-Fernández+L%22">Ortiz-Fernández L</searchLink>; Institute of Parasitology and Biomedicine López-Neyra, CSIC, Granada, Spain.
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  Data: <searchLink fieldCode="JN" term="%22100883501%22">Rheumatology (Oxford, England)</searchLink> [Rheumatology (Oxford)] 2026 May 05; Vol. 65 (5).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100883501 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1462-0332 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214620324%22">14620324 </searchLink><i>NLM ISO Abbreviation: </i>Rheumatology (Oxford) <i>Subsets: </i>MEDLINE
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