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Microbiomic and immunogenic biomarkers of adjuvant chemotherapy efficacy in stage III colorectal cancer.

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Title: Microbiomic and immunogenic biomarkers of adjuvant chemotherapy efficacy in stage III colorectal cancer.
Authors: Machida E; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama City, Saitama, Japan., Takamizawa Y; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Colorectal Surgery, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan., Takayanagi D; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-ku, Tokyo, Japan.; Division of Medical Oncology, Department of Medicine, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan., Cho H; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Genetic Medicine and Services, National Cancer Centre Hospital, Chuo-ku, Tokyo, Japan., Shida D; Department of Colorectal Surgery, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan., Yamada M; Endoscopy Division, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan., Asami Y; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan., Ono H; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan., Takeuchi M; Department of Diagnostic Pathology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan., Hamamoto R; Division of Medical AI Research and Development, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan., Rikiyama T; Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama City, Saitama, Japan., Suzuki K; Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama City, Saitama, Japan., Kanemitsu Y; Department of Colorectal Surgery, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan., Kohno T; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan., Takashima A; Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan., Sekine S; Division of Molecular Pathology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan., Shiraishi K; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Clinical Genomics, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.
Source: JNCI cancer spectrum [JNCI Cancer Spectr] 2026 May 09; Vol. 10 (3).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101721827 Publication Model: Print Cited Medium: Internet ISSN: 2515-5091 (Electronic) Linking ISSN: 25155091 NLM ISO Abbreviation: JNCI Cancer Spectr Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Machida+E%22">Machida E</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama City, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Takamizawa+Y%22">Takamizawa Y</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Colorectal Surgery, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takayanagi+D%22">Takayanagi D</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Clinical Diagnostic Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya-ku, Tokyo, Japan.; Division of Medical Oncology, Department of Medicine, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Cho+H%22">Cho H</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Genetic Medicine and Services, National Cancer Centre Hospital, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shida+D%22">Shida D</searchLink>; Department of Colorectal Surgery, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamada+M%22">Yamada M</searchLink>; Endoscopy Division, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Asami+Y%22">Asami Y</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ono+H%22">Ono H</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takeuchi+M%22">Takeuchi M</searchLink>; Department of Diagnostic Pathology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hamamoto+R%22">Hamamoto R</searchLink>; Division of Medical AI Research and Development, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Rikiyama+T%22">Rikiyama T</searchLink>; Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama City, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+K%22">Suzuki K</searchLink>; Department of Surgery, Saitama Medical Center, Jichi Medical University, Saitama City, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Kanemitsu+Y%22">Kanemitsu Y</searchLink>; Department of Colorectal Surgery, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kohno+T%22">Kohno T</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takashima+A%22">Takashima A</searchLink>; Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sekine+S%22">Sekine S</searchLink>; Division of Molecular Pathology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shiraishi+K%22">Shiraishi K</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Department of Clinical Genomics, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.
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