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Non-surgical casting versus surgical reduction for children with severely displaced distal radial fractures (the CRAFFT Study): a multicentre, randomised, controlled non-inferiority trial and economic evaluation.

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Title: Non-surgical casting versus surgical reduction for children with severely displaced distal radial fractures (the CRAFFT Study): a multicentre, randomised, controlled non-inferiority trial and economic evaluation.
Authors: Perry DC; Liverpool Institute of Child Health and Well Being, University of Liverpool, Liverpool, UK; Alder Hey Children's Hospital, Liverpool, UK; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK. Electronic address: danperry@liverpool.ac.uk., Zimmermann A; Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Achten J; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Nicolaou N; Sheffield Children's Hospital, Sheffield, UK., Metcalfe D; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Kounali D; Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Lyttle MD; Emergency Department, Bristol Royal Hospital for Children, Bristol, UK; Research in Emergency Care Avon Collaborative Hub (REACH), University of the West of England, Bristol, UK., Frempong S; Warwick Clinical Trials Unit, University of Warwick, Warwick, UK., Appelbe D; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Mason J; Warwick Clinical Trials Unit, University of Warwick, Warwick, UK., Kandiyali R; Warwick Clinical Trials Unit, University of Warwick, Warwick, UK., Gibson P; Wirral, Merseyside, UK., Costa ML; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Corporate Authors: CRAFFT Study Investigators (TOTS Research Collaborative and the PERUKI Network)
Source: Lancet (London, England) [Lancet] 2026 Apr 18; Vol. 407 (10538), pp. 1538-1548. Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Pragmatic Clinical Trial; Comparative Study; Equivalence Trial
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Non-surgical casting versus surgical reduction for children with severely displaced distal radial fractures (the CRAFFT Study): a multicentre, randomised, controlled non-inferiority trial and economic evaluation.
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  Data: <searchLink fieldCode="AU" term="%22Perry+DC%22">Perry DC</searchLink>; Liverpool Institute of Child Health and Well Being, University of Liverpool, Liverpool, UK; Alder Hey Children's Hospital, Liverpool, UK; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK. Electronic address: danperry@liverpool.ac.uk.<br /><searchLink fieldCode="AU" term="%22Zimmermann+A%22">Zimmermann A</searchLink>; Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Achten+J%22">Achten J</searchLink>; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Nicolaou+N%22">Nicolaou N</searchLink>; Sheffield Children's Hospital, Sheffield, UK.<br /><searchLink fieldCode="AU" term="%22Metcalfe+D%22">Metcalfe D</searchLink>; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kounali+D%22">Kounali D</searchLink>; Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lyttle+MD%22">Lyttle MD</searchLink>; Emergency Department, Bristol Royal Hospital for Children, Bristol, UK; Research in Emergency Care Avon Collaborative Hub (REACH), University of the West of England, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Frempong+S%22">Frempong S</searchLink>; Warwick Clinical Trials Unit, University of Warwick, Warwick, UK.<br /><searchLink fieldCode="AU" term="%22Appelbe+D%22">Appelbe D</searchLink>; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Mason+J%22">Mason J</searchLink>; Warwick Clinical Trials Unit, University of Warwick, Warwick, UK.<br /><searchLink fieldCode="AU" term="%22Kandiyali+R%22">Kandiyali R</searchLink>; Warwick Clinical Trials Unit, University of Warwick, Warwick, UK.<br /><searchLink fieldCode="AU" term="%22Gibson+P%22">Gibson P</searchLink>; Wirral, Merseyside, UK.<br /><searchLink fieldCode="AU" term="%22Costa+ML%22">Costa ML</searchLink>; Kadoorie Institute for Trauma, Emergency and Critical Care, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
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  Data: <searchLink fieldCode="JN" term="%222985213R%22">Lancet (London, England)</searchLink> [Lancet] 2026 Apr 18; Vol. 407 (10538), pp. 1538-1548. <i>Date of Electronic Publication: </i>2026 Apr 08.
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  Data: Journal Article; Multicenter Study; Randomized Controlled Trial; Pragmatic Clinical Trial; Comparative Study; Equivalence Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985213R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-547X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201406736%22">01406736 </searchLink><i>NLM ISO Abbreviation: </i>Lancet <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 18
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