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Development and validation of a precision treatment rules for first-line antipsychotic recommendations in first episode psychosis jointly incorporating effectiveness, side effects and patient preferences.

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Title: Development and validation of a precision treatment rules for first-line antipsychotic recommendations in first episode psychosis jointly incorporating effectiveness, side effects and patient preferences.
Authors: Krakowski K; Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy. kamil.krakowski01@universitadipavia.it.; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. kamil.krakowski01@universitadipavia.it., Oliver D; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Department of Psychiatry, University of Oxford, Oxford, UK.; NIHR Oxford Health Biomedical Research Centre, Oxford, UK.; OPEN Early Detection Service, Oxford Health NHS Foundation Trust, Oxford, UK., Arribas M; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Logeswaran Y; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., de Micheli A; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Patel R; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Department of Psychiatry, University of Cambridge, Cambridge, UK., Stahl D; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Fusar-Poli P; Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy.; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; OASIS Service, South London and the Maudsley National Health Service Foundation Trust, London, UK.; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University Munich, München, Germany.
Source: Translational psychiatry [Transl Psychiatry] 2026 Apr 11; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Krakowski+K%22">Krakowski K</searchLink>; Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy. kamil.krakowski01@universitadipavia.it.; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. kamil.krakowski01@universitadipavia.it.<br /><searchLink fieldCode="AU" term="%22Oliver+D%22">Oliver D</searchLink>; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Department of Psychiatry, University of Oxford, Oxford, UK.; NIHR Oxford Health Biomedical Research Centre, Oxford, UK.; OPEN Early Detection Service, Oxford Health NHS Foundation Trust, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Arribas+M%22">Arribas M</searchLink>; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Logeswaran+Y%22">Logeswaran Y</searchLink>; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22de+Micheli+A%22">de Micheli A</searchLink>; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Patel+R%22">Patel R</searchLink>; Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; Department of Psychiatry, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Stahl+D%22">Stahl D</searchLink>; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Fusar-Poli+P%22">Fusar-Poli P</searchLink>; Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy.; Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.; OASIS Service, South London and the Maudsley National Health Service Foundation Trust, London, UK.; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University Munich, München, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2026 Apr 11; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Apr 11.
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              Text: 2026 Apr 11
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