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Suppression of PP2A-B56α drives EMT in EGFR mutant non-small cell lung cancer.

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Title: Suppression of PP2A-B56α drives EMT in EGFR mutant non-small cell lung cancer.
Authors: Heil BN; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Baral G; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Pfeffer CM; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Bahler MB; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Gulavani SS; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Smith EG; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Gartenhaus LE; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Darling AK; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Clifford SJ; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Smith-Kinnaman W; Center for Proteome Analysis, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA., Hansen K; Center for Proteome Analysis, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA., Doud EH; Center for Proteome Analysis, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA.; Biochemistry and Molecular Biology, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA., Mall GK; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Hata AN; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Anderson NL; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA., Olson MR; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, USA., Allen-Petersen BL; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA. ballenpe@purdue.edu.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA. ballenpe@purdue.edu.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, USA. ballenpe@purdue.edu.
Source: Oncogene [Oncogene] 2026 Jun; Vol. 45 (20), pp. 1861-1873. Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
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  Data: Suppression of PP2A-B56α drives EMT in EGFR mutant non-small cell lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Heil+BN%22">Heil BN</searchLink>; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Baral+G%22">Baral G</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Pfeffer+CM%22">Pfeffer CM</searchLink>; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Bahler+MB%22">Bahler MB</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Gulavani+SS%22">Gulavani SS</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Smith+EG%22">Smith EG</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Gartenhaus+LE%22">Gartenhaus LE</searchLink>; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Darling+AK%22">Darling AK</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Clifford+SJ%22">Clifford SJ</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Smith-Kinnaman+W%22">Smith-Kinnaman W</searchLink>; Center for Proteome Analysis, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Hansen+K%22">Hansen K</searchLink>; Center for Proteome Analysis, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Doud+EH%22">Doud EH</searchLink>; Center for Proteome Analysis, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA.; Biochemistry and Molecular Biology, Indiana University School of Medicine (IUSM), Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Mall+GK%22">Mall GK</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Hata+AN%22">Hata AN</searchLink>; Massachusetts General Hospital Cancer Center, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+NL%22">Anderson NL</searchLink>; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Olson+MR%22">Olson MR</searchLink>; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Allen-Petersen+BL%22">Allen-Petersen BL</searchLink>; Purdue University Interdisciplinary Life Sciences Program (PULSe), Purdue University, West Lafayette, IN, USA. ballenpe@purdue.edu.; Department of Biological Sciences, Purdue University, West Lafayette, IN, USA. ballenpe@purdue.edu.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, IN, USA. ballenpe@purdue.edu.
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  Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2026 Jun; Vol. 45 (20), pp. 1861-1873. <i>Date of Electronic Publication: </i>2026 Apr 11.
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