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Advancing regenerative medicine with RNA nanotechnology for chronic and end organ diseases.

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Title: Advancing regenerative medicine with RNA nanotechnology for chronic and end organ diseases.
Authors: Bakrania A; Toronto General Hospital Research Institute, Toronto, ON, Canada.; Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Nguyen Lefebvre AT; Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.; Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada., de Vries R; Canadian Donation and Transplantation Research Program, Toronto, ON, Canada., Laflamme MA; McEwen Stem Cell Institute, University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada., Jaeckel E; Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.; Division of Gastroenterology, Department of Medicine, University Health Network and University of Toronto, Toronto, ON, Canada., Hansen He H; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Radvanyi L; Ontario Institute for Cancer Research, Toronto, ON, Canada., Hedtrich S; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.; Center of Biological Design, Berlin Institute of Health at Charite - Universitatsmedizin Berlin, Berlin, Germany.; Department of Infectious Diseases and Respiratory Medicine, Charite - Universitatsmedizin Berlin, Corporate member of Freie Universitat Berlin and Humboldt Universitat zu Berlin, Berlin, Germany.; Max-Delbruck Center for Molecular Medicine in the Helmholtz Associateion (MDC), Berlin, Germany., Sahay G; Department of Pharmaceutical Sciences, College of Pharmacy, Robertson Life Sciences Building, Oregon State University, Portland, OR, USA.; Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.; Department of Biomedical Engineering, Robertson Life Sciences Building, Oregon Health and Science University, Portland, OR, USA., Blakney A; Michael Smith Laboratories, School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada., Sefton M; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.; Institute Biomedical Engineering, University of Toronto, Toronto, ON, Canada., Li B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Institute Biomedical Engineering, University of Toronto, Toronto, ON, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada., Zheng G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Bhat M; Toronto General Hospital Research Institute, Toronto, ON, Canada. Mamatha.Bhat@uhn.ca.; Ajmera Transplant Program, University Health Network, Toronto, ON, Canada. Mamatha.Bhat@uhn.ca.; Division of Gastroenterology, Department of Medicine, University Health Network and University of Toronto, Toronto, ON, Canada. Mamatha.Bhat@uhn.ca.; Department of Medical Sciences, Toronto, ON, Canada. Mamatha.Bhat@uhn.ca.
Source: Communications medicine [Commun Med (Lond)] 2026 Apr 11; Vol. 6 (1). Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Portfolio Country of Publication: England NLM ID: 9918250414506676 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-664X (Electronic) Linking ISSN: 2730664X NLM ISO Abbreviation: Commun Med (Lond) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Advancing regenerative medicine with RNA nanotechnology for chronic and end organ diseases.
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  Data: <searchLink fieldCode="AU" term="%22Bakrania+A%22">Bakrania A</searchLink>; Toronto General Hospital Research Institute, Toronto, ON, Canada.; Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Nguyen+Lefebvre+AT%22">Nguyen Lefebvre AT</searchLink>; Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.; Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22de+Vries+R%22">de Vries R</searchLink>; Canadian Donation and Transplantation Research Program, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Laflamme+MA%22">Laflamme MA</searchLink>; McEwen Stem Cell Institute, University Health Network, Toronto, ON, Canada.; Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Jaeckel+E%22">Jaeckel E</searchLink>; Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.; Division of Gastroenterology, Department of Medicine, University Health Network and University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Hansen+He+H%22">Hansen He H</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Radvanyi+L%22">Radvanyi L</searchLink>; Ontario Institute for Cancer Research, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Hedtrich+S%22">Hedtrich S</searchLink>; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.; Center of Biological Design, Berlin Institute of Health at Charite - Universitatsmedizin Berlin, Berlin, Germany.; Department of Infectious Diseases and Respiratory Medicine, Charite - Universitatsmedizin Berlin, Corporate member of Freie Universitat Berlin and Humboldt Universitat zu Berlin, Berlin, Germany.; Max-Delbruck Center for Molecular Medicine in the Helmholtz Associateion (MDC), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Sahay+G%22">Sahay G</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy, Robertson Life Sciences Building, Oregon State University, Portland, OR, USA.; Department of Ophthalmology, Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA.; Department of Biomedical Engineering, Robertson Life Sciences Building, Oregon Health and Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Blakney+A%22">Blakney A</searchLink>; Michael Smith Laboratories, School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Sefton+M%22">Sefton M</searchLink>; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.; Institute Biomedical Engineering, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Institute Biomedical Engineering, University of Toronto, Toronto, ON, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Zheng+G%22">Zheng G</searchLink>; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Bhat+M%22">Bhat M</searchLink>; Toronto General Hospital Research Institute, Toronto, ON, Canada. Mamatha.Bhat@uhn.ca.; Ajmera Transplant Program, University Health Network, Toronto, ON, Canada. Mamatha.Bhat@uhn.ca.; Division of Gastroenterology, Department of Medicine, University Health Network and University of Toronto, Toronto, ON, Canada. Mamatha.Bhat@uhn.ca.; Department of Medical Sciences, Toronto, ON, Canada. Mamatha.Bhat@uhn.ca.
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        Value: 10.1038/s43856-026-01476-y
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