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Distinct metabolic signatures of Alzheimer's and Parkinson's disease revealed through genetic overlap.

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Title: Distinct metabolic signatures of Alzheimer's and Parkinson's disease revealed through genetic overlap.
Authors: Stinson SE; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: sstins@ous-hf.no., Shadrin AA; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway., Rahman Z; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Rødevand L; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Broce IJ; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, CA, USA; University of California San Diego, La Jolla, CA, USA., Selbæk G; Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway; The Norwegian National Centre for Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway., Stefansson H; AMGEN deCODE Genetics, Reykjavik, Iceland., Haavik J; Department of Biomedicine, Faculty of Medicine, University of Bergen, Bergen, Norway; Division of Psychiatry, Haukeland University Hospital, Bergen, Norway., Parker N; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Koch E; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Frei O; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway., O'Connell KS; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Smeland OB; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Djurovic S; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Medical Genetics, Oslo University Hospital & University of Oslo, Oslo, Norway., Dale AM; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, CA, USA; University of California San Diego, La Jolla, CA, USA., van der Meer D; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Andreassen OA; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway. Electronic address: ole.andreassen@medisin.uio.no.
Source: EBioMedicine [EBioMedicine] 2026 May; Vol. 127, pp. 106254. Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: Distinct metabolic signatures of Alzheimer's and Parkinson's disease revealed through genetic overlap.
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  Data: <searchLink fieldCode="AU" term="%22Stinson+SE%22">Stinson SE</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: sstins@ous-hf.no.<br /><searchLink fieldCode="AU" term="%22Shadrin+AA%22">Shadrin AA</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Rahman+Z%22">Rahman Z</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Rødevand+L%22">Rødevand L</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Broce+IJ%22">Broce IJ</searchLink>; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, CA, USA; University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Selbæk+G%22">Selbæk G</searchLink>; Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway; The Norwegian National Centre for Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway.<br /><searchLink fieldCode="AU" term="%22Stefansson+H%22">Stefansson H</searchLink>; AMGEN deCODE Genetics, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Haavik+J%22">Haavik J</searchLink>; Department of Biomedicine, Faculty of Medicine, University of Bergen, Bergen, Norway; Division of Psychiatry, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Parker+N%22">Parker N</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Koch+E%22">Koch E</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Frei+O%22">Frei O</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22O'Connell+KS%22">O'Connell KS</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Smeland+OB%22">Smeland OB</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Djurovic+S%22">Djurovic S</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Medical Genetics, Oslo University Hospital & University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Dale+AM%22">Dale AM</searchLink>; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, CA, USA; University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22van+der+Meer+D%22">van der Meer D</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Andreassen+OA%22">Andreassen OA</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway. Electronic address: ole.andreassen@medisin.uio.no.
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