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Desert Immune Phenotype in Endometrial Carcinoma: A Distinct Subgroup With Poor Prognosis and Targetable Mutations.

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Title: Desert Immune Phenotype in Endometrial Carcinoma: A Distinct Subgroup With Poor Prognosis and Targetable Mutations.
Authors: Kaya M; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Lin LH; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Oosting J; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Powell ME; Department of Clinical Oncology, Barts and The London NHS Trust, London, United Kingdom., Davidson EJ; Gynaecological Oncology Research Group, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St. Mary's Hospital, Manchester, United Kingdom; Department of Obstetrics and Gynaecology, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom; Centre for Reproductive Health, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK; CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Leary A; Department of Medical Oncology, Gustave Roussy, Villejuif, France., Mileshkin LR; Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia., Shepherd L; Department of Pathology and Molecular Medicine, Queen's University, Kingston, Ontario, Canada., de Bruyn M; Department of Obstetrics and Gynaecology, University Medical Centre Groningen, Groningen, The Netherlands., Jobsen J; Department of Radiation Oncology, Medisch Spectrum Twente, Enschede, The Netherlands., Kroep JR; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands., Creutzberg CL; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands., Horeweg N; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands., Léon-Castillo A; Department of Pathology, Antoni van Leeuwenhoek, Amsterdam, The Netherlands., Parra-Herran C; Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Smit VTHBM; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Nucci MR; Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Bosse T; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: T.Bosse@lumc.nl.
Source: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2026 Jun; Vol. 39 (6), pp. 101000. Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 8806605 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0285 (Electronic) Linking ISSN: 08933952 NLM ISO Abbreviation: Mod Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Desert Immune Phenotype in Endometrial Carcinoma: A Distinct Subgroup With Poor Prognosis and Targetable Mutations.
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  Data: <searchLink fieldCode="AU" term="%22Kaya+M%22">Kaya M</searchLink>; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lin+LH%22">Lin LH</searchLink>; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Oosting+J%22">Oosting J</searchLink>; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Powell+ME%22">Powell ME</searchLink>; Department of Clinical Oncology, Barts and The London NHS Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Davidson+EJ%22">Davidson EJ</searchLink>; Gynaecological Oncology Research Group, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St. Mary's Hospital, Manchester, United Kingdom; Department of Obstetrics and Gynaecology, St. Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom; Centre for Reproductive Health, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK; CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Leary+A%22">Leary A</searchLink>; Department of Medical Oncology, Gustave Roussy, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Mileshkin+LR%22">Mileshkin LR</searchLink>; Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Shepherd+L%22">Shepherd L</searchLink>; Department of Pathology and Molecular Medicine, Queen's University, Kingston, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22de+Bruyn+M%22">de Bruyn M</searchLink>; Department of Obstetrics and Gynaecology, University Medical Centre Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jobsen+J%22">Jobsen J</searchLink>; Department of Radiation Oncology, Medisch Spectrum Twente, Enschede, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kroep+JR%22">Kroep JR</searchLink>; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Creutzberg+CL%22">Creutzberg CL</searchLink>; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Horeweg+N%22">Horeweg N</searchLink>; Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Léon-Castillo+A%22">Léon-Castillo A</searchLink>; Department of Pathology, Antoni van Leeuwenhoek, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Parra-Herran+C%22">Parra-Herran C</searchLink>; Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Smit+VTHBM%22">Smit VTHBM</searchLink>; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nucci+MR%22">Nucci MR</searchLink>; Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Bosse+T%22">Bosse T</searchLink>; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: T.Bosse@lumc.nl.
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      – TitleFull: Desert Immune Phenotype in Endometrial Carcinoma: A Distinct Subgroup With Poor Prognosis and Targetable Mutations.
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