UV1 plus pembrolizumab in recurrent and metastatic head and neck squamous cell carcinoma: safe, immunogenic, but lacking efficacy.

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Title: UV1 plus pembrolizumab in recurrent and metastatic head and neck squamous cell carcinoma: safe, immunogenic, but lacking efficacy.
Authors: Flores G; Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.; Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IA, USA., Buchakjian MR; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA., Heft Neal M; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA., Brenner JC; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
Source: Translational cancer research [Transl Cancer Res] 2026 Mar 31; Vol. 15 (3), pp. 140. Date of Electronic Publication: 2026 Mar 24.
Publication Type: Editorial; Comment
Journal Info: Publisher: Pioneer Bioscience Publishing Company Country of Publication: China NLM ID: 101585958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2219-6803 (Electronic) Linking ISSN: 2218676X NLM ISO Abbreviation: Transl Cancer Res Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41969436
AccessLevel: 2
PubType: Editorial & Opinion
PubTypeId: editorialOpinion
PreciseRelevancyScore: 0
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  Data: UV1 plus pembrolizumab in recurrent and metastatic head and neck squamous cell carcinoma: safe, immunogenic, but lacking efficacy.
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  Data: <searchLink fieldCode="AU" term="%22Flores+G%22">Flores G</searchLink>; Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.; Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Buchakjian+MR%22">Buchakjian MR</searchLink>; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Heft+Neal+M%22">Heft Neal M</searchLink>; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Brenner+JC%22">Brenner JC</searchLink>; Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.
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  Data: <searchLink fieldCode="JN" term="%22101585958%22">Translational cancer research</searchLink> [Transl Cancer Res] 2026 Mar 31; Vol. 15 (3), pp. 140. <i>Date of Electronic Publication: </i>2026 Mar 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Pioneer+Bioscience+Publishing+Company%22">Pioneer Bioscience Publishing Company </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101585958 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2219-6803 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222218676X%22">2218676X </searchLink><i>NLM ISO Abbreviation: </i>Transl Cancer Res <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41969436
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      – Type: doi
        Value: 10.21037/tcr-2025-1-2689
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      – Code: eng
        Text: English
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      – TitleFull: UV1 plus pembrolizumab in recurrent and metastatic head and neck squamous cell carcinoma: safe, immunogenic, but lacking efficacy.
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            NameFull: Buchakjian MR
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            – D: 31
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              Text: 2026 Mar 31
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              Y: 2026
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