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Panax notoginseng flower protects against diabetic cardiomyopathy by regulating the ACSL4/ALOX15 pathway.

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Title: Panax notoginseng flower protects against diabetic cardiomyopathy by regulating the ACSL4/ALOX15 pathway.
Authors: Zhou Y; Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Ouyang L; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China., Dong L; Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Zhang X; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China., Du J; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China., Sun S; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China., Ussher JR; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada., Chan JSF; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada., Chen L; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China., Huang D; Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China., Li Y; Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 Mar 27; Vol. 17, pp. 1780442. Date of Electronic Publication: 2026 Mar 27 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Panax notoginseng flower protects against diabetic cardiomyopathy by regulating the ACSL4/ALOX15 pathway.
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  Data: <searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ouyang+L%22">Ouyang L</searchLink>; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Dong+L%22">Dong L</searchLink>; Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Du+J%22">Du J</searchLink>; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+S%22">Sun S</searchLink>; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ussher+JR%22">Ussher JR</searchLink>; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Chan+JSF%22">Chan JSF</searchLink>; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Healthy Aging Research Center, Amway (Shanghai) Innovation and Science Co., Ltd., Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Huang+D%22">Huang D</searchLink>; Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of TCM Chemistry, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2026 Mar 27; Vol. 17, pp. 1780442. <i>Date of Electronic Publication: </i>2026 Mar 27 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fphar.2026.1780442
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              Text: 2026 Mar 27
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