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Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase antibodies.

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Title: Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase antibodies.
Authors: Singh G; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Bhavsar D; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Hermann E; Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna, Vienna, Austria., Gleason C; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Singh Sandhu H; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Singh P; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Nardulli JR; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Lyttle N; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Chen Y; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Sabaiduc S; Immunization Programs and Vaccine Preventable Diseases Service, BC Centre for Disease Control, Vancouver, British Columbia, Canada., Peña Alzua G; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Skowronski DM; Immunization Programs and Vaccine Preventable Diseases Service, BC Centre for Disease Control, Vancouver, British Columbia, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada., Simon V; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; The Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna, Vienna, Austria.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Ludwig Boltzmann Institute for Science Outreach and Pandemic Preparedness at the Medical University of Vienna, Vienna, Austria.
Source: MBio [mBio] 2026 May 13; Vol. 17 (5), pp. e0044526. Date of Electronic Publication: 2026 Apr 13.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
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  Data: Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase antibodies.
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  Data: <searchLink fieldCode="AU" term="%22Singh+G%22">Singh G</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Bhavsar+D%22">Bhavsar D</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Hermann+E%22">Hermann E</searchLink>; Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Gleason+C%22">Gleason C</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Singh+Sandhu+H%22">Singh Sandhu H</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Singh+P%22">Singh P</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Nardulli+JR%22">Nardulli JR</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Lyttle+N%22">Lyttle N</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Sabaiduc+S%22">Sabaiduc S</searchLink>; Immunization Programs and Vaccine Preventable Diseases Service, BC Centre for Disease Control, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Peña+Alzua+G%22">Peña Alzua G</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Skowronski+DM%22">Skowronski DM</searchLink>; Immunization Programs and Vaccine Preventable Diseases Service, BC Centre for Disease Control, Vancouver, British Columbia, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Simon+V%22">Simon V</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; The Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Krammer+F%22">Krammer F</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna, Vienna, Austria.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.; Ludwig Boltzmann Institute for Science Outreach and Pandemic Preparedness at the Medical University of Vienna, Vienna, Austria.
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