View in EDS

Data-driven modelling of tau pathology reveals distinct progressive supranuclear palsy subtypes.

Saved in:
Bibliographic Details
Title: Data-driven modelling of tau pathology reveals distinct progressive supranuclear palsy subtypes.
Authors: Cullinane PW; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Queen Square Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK., Parmera JB; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Department of Neurology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, 05402 000, Brazil., Nelvagal H; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Curless T; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Paras Chajed L; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Wrigley S; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Sifontes Valladares W; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Burrows M; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Ebanks K; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Wu L; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK., Binding LP; UCL Hawkes Institute and Department of Computer Science, University College London, London, WC1V 6LJ, UK., Anton J; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Revesz T; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK., Real R; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK., Vaughan DP; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK., Jabbari E; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK., Morris HR; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK., Brandner S; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.; Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK., Young AL; UCL Hawkes Institute and Department of Computer Science, University College London, London, WC1V 6LJ, UK., Hoti G; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Ma Y; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Bechtawi M; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., Chiraki N; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK., de Pablo-Fernández E; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Centre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University London, EC1M 6BQ, UK., Lim YM; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.; Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK., Warner TT; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Queen Square Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK., Jaunmuktane Z; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.
Source: Brain : a journal of neurology [Brain] 2026 Apr 13. Date of Electronic Publication: 2026 Apr 13.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41974128
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Data-driven modelling of tau pathology reveals distinct progressive supranuclear palsy subtypes.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Cullinane+PW%22">Cullinane PW</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Queen Square Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Parmera+JB%22">Parmera JB</searchLink>; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Department of Neurology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, 05402 000, Brazil.<br /><searchLink fieldCode="AU" term="%22Nelvagal+H%22">Nelvagal H</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Curless+T%22">Curless T</searchLink>; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Paras+Chajed+L%22">Paras Chajed L</searchLink>; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Wrigley+S%22">Wrigley S</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Sifontes+Valladares+W%22">Sifontes Valladares W</searchLink>; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Burrows+M%22">Burrows M</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Ebanks+K%22">Ebanks K</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Binding+LP%22">Binding LP</searchLink>; UCL Hawkes Institute and Department of Computer Science, University College London, London, WC1V 6LJ, UK.<br /><searchLink fieldCode="AU" term="%22Anton+J%22">Anton J</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Revesz+T%22">Revesz T</searchLink>; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Real+R%22">Real R</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Vaughan+DP%22">Vaughan DP</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Jabbari+E%22">Jabbari E</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Morris+HR%22">Morris HR</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Brandner+S%22">Brandner S</searchLink>; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.; Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Young+AL%22">Young AL</searchLink>; UCL Hawkes Institute and Department of Computer Science, University College London, London, WC1V 6LJ, UK.<br /><searchLink fieldCode="AU" term="%22Hoti+G%22">Hoti G</searchLink>; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Ma+Y%22">Ma Y</searchLink>; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Bechtawi+M%22">Bechtawi M</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22Chiraki+N%22">Chiraki N</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.<br /><searchLink fieldCode="AU" term="%22de+Pablo-Fernández+E%22">de Pablo-Fernández E</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Centre for Preventive Neurology, Wolfson Institute of Population Health, Queen Mary University London, EC1M 6BQ, UK.<br /><searchLink fieldCode="AU" term="%22Lim+YM%22">Lim YM</searchLink>; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.; Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Warner+TT%22">Warner TT</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Queen Square Movement Disorders Centre, UCL Queen Square Institute of Neurology, London, WC1N 3BG, UK.<br /><searchLink fieldCode="AU" term="%22Jaunmuktane+Z%22">Jaunmuktane Z</searchLink>; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, WC1N 3BG, UK.; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, WC1N 1PJ, UK.; Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220372537%22">Brain : a journal of neurology</searchLink> [Brain] 2026 Apr 13. <i>Date of Electronic Publication: </i>2026 Apr 13.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372537 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2156 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200068950%22">00068950 </searchLink><i>NLM ISO Abbreviation: </i>Brain <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41974128
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1093/brain/awag131
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Data-driven modelling of tau pathology reveals distinct progressive supranuclear palsy subtypes.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Cullinane PW
      – PersonEntity:
          Name:
            NameFull: Parmera JB
      – PersonEntity:
          Name:
            NameFull: Nelvagal H
      – PersonEntity:
          Name:
            NameFull: Curless T
      – PersonEntity:
          Name:
            NameFull: Paras Chajed L
      – PersonEntity:
          Name:
            NameFull: Wrigley S
      – PersonEntity:
          Name:
            NameFull: Sifontes Valladares W
      – PersonEntity:
          Name:
            NameFull: Burrows M
      – PersonEntity:
          Name:
            NameFull: Ebanks K
      – PersonEntity:
          Name:
            NameFull: Wu L
      – PersonEntity:
          Name:
            NameFull: Binding LP
      – PersonEntity:
          Name:
            NameFull: Anton J
      – PersonEntity:
          Name:
            NameFull: Revesz T
      – PersonEntity:
          Name:
            NameFull: Real R
      – PersonEntity:
          Name:
            NameFull: Vaughan DP
      – PersonEntity:
          Name:
            NameFull: Jabbari E
      – PersonEntity:
          Name:
            NameFull: Morris HR
      – PersonEntity:
          Name:
            NameFull: Brandner S
      – PersonEntity:
          Name:
            NameFull: Young AL
      – PersonEntity:
          Name:
            NameFull: Hoti G
      – PersonEntity:
          Name:
            NameFull: Ma Y
      – PersonEntity:
          Name:
            NameFull: Bechtawi M
      – PersonEntity:
          Name:
            NameFull: Chiraki N
      – PersonEntity:
          Name:
            NameFull: de Pablo-Fernández E
      – PersonEntity:
          Name:
            NameFull: Lim YM
      – PersonEntity:
          Name:
            NameFull: Warner TT
      – PersonEntity:
          Name:
            NameFull: Jaunmuktane Z
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 04
              Text: 2026 Apr 13
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1460-2156
          Titles:
            – TitleFull: Brain : a journal of neurology
              Type: main
ResultId 1