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Staphylococcus aureus biofilm extracellular DNA neutralizes the antimicrobial activity of histone H3.

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Title: Staphylococcus aureus biofilm extracellular DNA neutralizes the antimicrobial activity of histone H3.
Authors: Rana PSJB; Department of Microbiology, The Ohio State University, Columbus, OH, USA.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA., Foley JR; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA., Bhattacharya M; Department of Microbiology, The Ohio State University, Columbus, OH, USA.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA., Gloag ES; Department of Biomedical Sciences and Pathobiology, Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA., Wozniak DJ; Department of Microbiology, The Ohio State University, Columbus, OH, USA. Daniel.Wozniak@osumc.edu.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA. Daniel.Wozniak@osumc.edu.
Source: NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2026 Apr 13; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Electronic Cited Medium: Internet ISSN: 2055-5008 (Electronic) Linking ISSN: 20555008 NLM ISO Abbreviation: NPJ Biofilms Microbiomes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Staphylococcus aureus biofilm extracellular DNA neutralizes the antimicrobial activity of histone H3.
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  Data: <searchLink fieldCode="AU" term="%22Rana+PSJB%22">Rana PSJB</searchLink>; Department of Microbiology, The Ohio State University, Columbus, OH, USA.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Foley+JR%22">Foley JR</searchLink>; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Bhattacharya+M%22">Bhattacharya M</searchLink>; Department of Microbiology, The Ohio State University, Columbus, OH, USA.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Gloag+ES%22">Gloag ES</searchLink>; Department of Biomedical Sciences and Pathobiology, Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.<br /><searchLink fieldCode="AU" term="%22Wozniak+DJ%22">Wozniak DJ</searchLink>; Department of Microbiology, The Ohio State University, Columbus, OH, USA. Daniel.Wozniak@osumc.edu.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA. Daniel.Wozniak@osumc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101666944%22">NPJ biofilms and microbiomes</searchLink> [NPJ Biofilms Microbiomes] 2026 Apr 13; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Apr 13.
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        Value: 10.1038/s41522-026-00979-9
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