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Distinct Ca2+ pools regulate NADPH oxidase 2 activation driving Ca2+-independent mitochondrial ROS formation and mitochondrial permeability transition in arsenic trioxide-treated NB4 cells.

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Title: Distinct Ca2+ pools regulate NADPH oxidase 2 activation driving Ca2+-independent mitochondrial ROS formation and mitochondrial permeability transition in arsenic trioxide-treated NB4 cells.
Authors: Guidarelli A; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy. andrea.guidarelli@uniurb.it., Spina A; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy., Buffi G; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy., Fiorani M; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy., Cantoni O; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy.
Source: Archives of toxicology [Arch Toxicol] 2026 Jul; Vol. 100 (7), pp. 2995-3010. Date of Electronic Publication: 2026 Apr 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Distinct Ca<superscript>2+</superscript> pools regulate NADPH oxidase 2 activation driving Ca<superscript>2+</superscript>-independent mitochondrial ROS formation and mitochondrial permeability transition in arsenic trioxide-treated NB4 cells.
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  Data: <searchLink fieldCode="AU" term="%22Guidarelli+A%22">Guidarelli A</searchLink>; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy. andrea.guidarelli@uniurb.it.<br /><searchLink fieldCode="AU" term="%22Spina+A%22">Spina A</searchLink>; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy.<br /><searchLink fieldCode="AU" term="%22Buffi+G%22">Buffi G</searchLink>; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy.<br /><searchLink fieldCode="AU" term="%22Fiorani+M%22">Fiorani M</searchLink>; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy.<br /><searchLink fieldCode="AU" term="%22Cantoni+O%22">Cantoni O</searchLink>; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy.
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  Data: <searchLink fieldCode="JN" term="%220417615%22">Archives of toxicology</searchLink> [Arch Toxicol] 2026 Jul; Vol. 100 (7), pp. 2995-3010. <i>Date of Electronic Publication: </i>2026 Apr 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0417615 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0738 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203405761%22">03405761 </searchLink><i>NLM ISO Abbreviation: </i>Arch Toxicol <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1007/s00204-026-04328-9
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      – Code: eng
        Text: English
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        StartPage: 2995
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      – TitleFull: Distinct Ca2+ pools regulate NADPH oxidase 2 activation driving Ca2+-independent mitochondrial ROS formation and mitochondrial permeability transition in arsenic trioxide-treated NB4 cells.
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            NameFull: Guidarelli A
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            NameFull: Spina A
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            NameFull: Buffi G
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            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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              Value: 7
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