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Biological, antimicrobial, and apical tissue dissolution effects of ambroxol hydrochloride as an irrigant for regenerative endodontics: an in vitro study.

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Title: Biological, antimicrobial, and apical tissue dissolution effects of ambroxol hydrochloride as an irrigant for regenerative endodontics: an in vitro study.
Authors: Coelho LAS; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil. letycia.coelho@usp.br.; Departament of Dentistry, Endodontics and Dental Materials, University of São Paulo, Al. Octávio Pinheiro Brizolla 9-75, Vila Universitária, Bauru, SP17012-901, Brazil. letycia.coelho@usp.br., Bordini EAF; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.; Present address: Department of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo, Ribeirão Preto, SP, Brazil., Cassiano FB; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil., Barros MC; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil., Silva RM; Department of Endodontics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA., de Andrade FB; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil., Soares DG; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil., Duarte MAH; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Source: BMC oral health [BMC Oral Health] 2026 Apr 14; Vol. 26 (1). Date of Electronic Publication: 2026 Apr 14.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088684 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6831 (Electronic) Linking ISSN: 14726831 NLM ISO Abbreviation: BMC Oral Health Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Biological, antimicrobial, and apical tissue dissolution effects of ambroxol hydrochloride as an irrigant for regenerative endodontics: an in vitro study.
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  Data: <searchLink fieldCode="AU" term="%22Coelho+LAS%22">Coelho LAS</searchLink>; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil. letycia.coelho@usp.br.; Departament of Dentistry, Endodontics and Dental Materials, University of São Paulo, Al. Octávio Pinheiro Brizolla 9-75, Vila Universitária, Bauru, SP17012-901, Brazil. letycia.coelho@usp.br.<br /><searchLink fieldCode="AU" term="%22Bordini+EAF%22">Bordini EAF</searchLink>; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.; Present address: Department of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo, Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Cassiano+FB%22">Cassiano FB</searchLink>; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Barros+MC%22">Barros MC</searchLink>; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+RM%22">Silva RM</searchLink>; Department of Endodontics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22de+Andrade+FB%22">de Andrade FB</searchLink>; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Soares+DG%22">Soares DG</searchLink>; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Duarte+MAH%22">Duarte MAH</searchLink>; Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22101088684%22">BMC oral health</searchLink> [BMC Oral Health] 2026 Apr 14; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 Apr 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101088684 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1472-6831 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214726831%22">14726831 </searchLink><i>NLM ISO Abbreviation: </i>BMC Oral Health <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12903-026-08297-4
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              Text: 2026 Apr 14
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