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LIN28A‒let-7b axis drives the aggressive and proinflammatory phenotype of rheumatoid arthritis fibroblast-like synoviocytes.

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Title: LIN28A‒let-7b axis drives the aggressive and proinflammatory phenotype of rheumatoid arthritis fibroblast-like synoviocytes.
Authors: Chae HY; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea., Yi K; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.; Preclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, 41061, Republic of Korea., Lim SG; Core Protein Resources Center, DGIST, Daegu, Republic of Korea., Park JY; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.; Core Protein Resources Center, DGIST, Daegu, Republic of Korea., Hyung H; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea., Kim SY; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea., Kim W; Department of Biochemistry, Department of Convergence Medical Science, and Institute of Medical Science, Gyeongsang National University College of Medicine, Jinju, Republic of Korea., Lee SI; Division of Rheumatology, Department of Internal Medicine and Institute of Medical Science,, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Jinju, Republic of Korea., Choi DK; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea., Kim MO; Department of Animal Science and Biotechnology, Research Institute for Innovative Animal Science, Kyungpook National University, Sangju, 37224, Republic of Korea., Ryoo ZY; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea. jaewoong64@knu.ac.kr.; Department of Animal Science and Biotechnology, Research Institute for Innovative Animal Science, Kyungpook National University, Sangju, 37224, Republic of Korea. jaewoong64@knu.ac.kr., Ko J; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea. jiwon.ko93@dgist.ac.kr.; Core Protein Resources Center, DGIST, Daegu, Republic of Korea. jiwon.ko93@dgist.ac.kr., Jang S; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea. soyun119@knu.ac.kr.; Institute of Life Science and Biotechnology, Kyungpook National University, Daegu, 41566, Republic of Korea. soyun119@knu.ac.kr.
Source: Arthritis research & therapy [Arthritis Res Ther] 2026 Apr 13; Vol. 28 (1). Date of Electronic Publication: 2026 Apr 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362 (Electronic) Linking ISSN: 14786354 NLM ISO Abbreviation: Arthritis Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: LIN28A‒let-7b axis drives the aggressive and proinflammatory phenotype of rheumatoid arthritis fibroblast-like synoviocytes.
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  Data: <searchLink fieldCode="AU" term="%22Chae+HY%22">Chae HY</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yi+K%22">Yi K</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.; Preclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, 41061, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+SG%22">Lim SG</searchLink>; Core Protein Resources Center, DGIST, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+JY%22">Park JY</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.; Core Protein Resources Center, DGIST, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hyung+H%22">Hyung H</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SY%22">Kim SY</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+W%22">Kim W</searchLink>; Department of Biochemistry, Department of Convergence Medical Science, and Institute of Medical Science, Gyeongsang National University College of Medicine, Jinju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SI%22">Lee SI</searchLink>; Division of Rheumatology, Department of Internal Medicine and Institute of Medical Science,, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Jinju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+DK%22">Choi DK</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MO%22">Kim MO</searchLink>; Department of Animal Science and Biotechnology, Research Institute for Innovative Animal Science, Kyungpook National University, Sangju, 37224, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryoo+ZY%22">Ryoo ZY</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea. jaewoong64@knu.ac.kr.; Department of Animal Science and Biotechnology, Research Institute for Innovative Animal Science, Kyungpook National University, Sangju, 37224, Republic of Korea. jaewoong64@knu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Ko+J%22">Ko J</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea. jiwon.ko93@dgist.ac.kr.; Core Protein Resources Center, DGIST, Daegu, Republic of Korea. jiwon.ko93@dgist.ac.kr.<br /><searchLink fieldCode="AU" term="%22Jang+S%22">Jang S</searchLink>; School of Life Sciences, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Republic of Korea. soyun119@knu.ac.kr.; Institute of Life Science and Biotechnology, Kyungpook National University, Daegu, 41566, Republic of Korea. soyun119@knu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101154438%22">Arthritis research & therapy</searchLink> [Arthritis Res Ther] 2026 Apr 13; Vol. 28 (1). <i>Date of Electronic Publication: </i>2026 Apr 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101154438 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-6362 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214786354%22">14786354 </searchLink><i>NLM ISO Abbreviation: </i>Arthritis Res Ther <i>Subsets: </i>MEDLINE
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      – TitleFull: LIN28A‒let-7b axis drives the aggressive and proinflammatory phenotype of rheumatoid arthritis fibroblast-like synoviocytes.
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              Text: 2026 Apr 13
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