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Naproxen and Ibuprofen Exposure Alter the Blood-Testis Barrier in a Novel In Vitro Model.

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Title: Naproxen and Ibuprofen Exposure Alter the Blood-Testis Barrier in a Novel In Vitro Model.
Authors: Crow KMS; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA., Cho IK; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA., Edenfield RC; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA., Easley KF; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA., Planinić A; Centre of Excellence for Reproductive and Regenerative Medicine, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia., Younis N; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Pittsburgh Development Center, Division of Developmental & Regenerative Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Waters E; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA., McClellan JS; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA., Zielen AC; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Tager K; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA., Castro C; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Simerly C; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Pittsburgh Development Center, Division of Developmental & Regenerative Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Orwig KE; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Ježek D; Centre of Excellence for Reproductive and Regenerative Medicine, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia., Koval M; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.; Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA., Easley CA 4th; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Mar 26; Vol. 27 (7). Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Naproxen and Ibuprofen Exposure Alter the Blood-Testis Barrier in a Novel In Vitro Model.
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  Data: <searchLink fieldCode="AU" term="%22Crow+KMS%22">Crow KMS</searchLink>; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA.<br /><searchLink fieldCode="AU" term="%22Cho+IK%22">Cho IK</searchLink>; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA.<br /><searchLink fieldCode="AU" term="%22Edenfield+RC%22">Edenfield RC</searchLink>; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA.<br /><searchLink fieldCode="AU" term="%22Easley+KF%22">Easley KF</searchLink>; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Planinić+A%22">Planinić A</searchLink>; Centre of Excellence for Reproductive and Regenerative Medicine, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Younis+N%22">Younis N</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Pittsburgh Development Center, Division of Developmental & Regenerative Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Waters+E%22">Waters E</searchLink>; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA.<br /><searchLink fieldCode="AU" term="%22McClellan+JS%22">McClellan JS</searchLink>; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA.<br /><searchLink fieldCode="AU" term="%22Zielen+AC%22">Zielen AC</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Tager+K%22">Tager K</searchLink>; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA.<br /><searchLink fieldCode="AU" term="%22Castro+C%22">Castro C</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Simerly+C%22">Simerly C</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.; Pittsburgh Development Center, Division of Developmental & Regenerative Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Orwig+KE%22">Orwig KE</searchLink>; Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Ježek+D%22">Ježek D</searchLink>; Centre of Excellence for Reproductive and Regenerative Medicine, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Koval+M%22">Koval M</searchLink>; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.; Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Easley+CA+4th%22">Easley CA 4th</searchLink>; Department of Environmental Health Science, College of Public Health, University of Georgia, Athens, GA 30602, USA.; Regenerative Bioscience Center, University of Georgia, Athens, GA 30602, USA.
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