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Updated consensus guidelines for the diagnosis and management of patients with HCL and HCL variant.

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Title: Updated consensus guidelines for the diagnosis and management of patients with HCL and HCL variant.
Authors: Zent CS; Department of Medicine and Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY., Tiacci E; Institute of Hematology and Center for Hemato-Oncological Research, University of Perugia and Santa Maria Della Misericordia Hospital, Perugia, Italy., Kreitman RJ; Laboratory of Molecular Biology, Centers for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD., Tadmor T; Hematology Unit, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel., Tallman MS; Memorial Sloan Kettering Cancer Center, New York, NY., Wörmann B; Charité-Universitätsmedizin Berlin, Berlin, Germany., Andritsos LA; University of New Mexico Comprehensive Cancer Center, Albuquerque, NM., Arons E; Laboratory of Molecular Biology, Centers for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD., Banerji V; Paul Albrechtsen Research Institute and Department of Medical Oncology & Hematology, CancerCare Manitoba, and Department of Internal Medicine, Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada., Barrientos JC; Mount Sinai Comprehensive Cancer Center, Miami Beach, FL., Bhat SA; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH., Blachly JS; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH.; Department of Biomedical Informatics, The Ohio State University, Columbus, OH., Broccoli A; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia 'Seràgnoli,' Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy., Call TG; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Dearden C; Royal Marsden NHS Foundation Trust, Sutton, United Kingdom., Demeter J; University, Faculty of Medicine, Department of Internal Medicine and Oncology, Budapest, Hungary., Dietrich S; University Hospital of Düsseldorf, Düsseldorf, Germany., El-Sharkawi D; Royal Marsden NHS Foundation Trust, Sutton, United Kingdom.; UK Institute of Cancer Research, Sutton, United Kingdom., Fagarasanu A; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada., Falini B; Institute of Hematology and Center for Hemato-Oncological Research, University of Perugia and Santa Maria Della Misericordia Hospital, Perugia, Italy., Forconi F; Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; Haematology Department, Cancer Care Directorate, University Hospital Southampton NHS Trust, Southampton, United Kingdom., Gerrie AS; BC Cancer Centre for Lymphoid Cancer, University of British Columbia, Vancouver, BC, Canada., Gladstone DE; Northwell, New Hyde Park, NY.; Northwell Health Cancer Institute, Lake Success, NY., Gozzetti A; Department of Medicine Surgery and Neurosciences, University of Siena, Siena, Italy., Hampel PJ; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Hermel DJ; Division of Hematology and Oncology, Scripps Clinic Medical Group, La Jolla, CA., Iyengar S; Royal Marsden NHS Foundation Trust, Sutton, United Kingdom., Johnston JB; Paul Albrechtsen Research Institute and Department of Medical Oncology & Hematology, CancerCare Manitoba, and Department of Internal Medicine, Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada., Juliusson G; Lund University Cancer Center, Lund, Sweden., Kipps TJ; Department of Medicine, Moores Cancer Center, University of California, San Diego, CA., Lauria F; University of Siena, Siena, Italy., Lozanski G; Department of Pathology, The Ohio State University Medical School, Columbus, OH., Parikh SA; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Park JH; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Polliack A; Hadassah Hebrew University Medical Center, Jerusalem, Israel., Quest G; Department of Pathology and Molecular Medicine, Kingston Health Sciences Centre and Queen's University, Kingston, ON, Canada., Rai K; Feinstein Institutes for Medical Research, Manhasset, NY., Ravandi F; The University of Texas MD Anderson Cancer Center, Houston, TX., Robak T; Department of Hematology, Medical University of Lodz, Lodz, Poland.; Department of General Hematology and Internal Medicine, Copernicus Hospital, Lodz, Poland., Rogers KA; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH., Saven A; Division of Hematology and Oncology, Scripps Clinic Medical Group, La Jolla, CA., Seymour JF; Department of Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, VIC, Australia.; Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, VIC, Australia., Tam CS; Department of Haematology, Alfred Hospital and Monash University, Melbourne, VIC, Australia., Troussard X; Hématologie, CHU de Caen, Caen, France., Zenz T; Department of Medical Oncology and Haematology, University Hospital and University of Zurich, Zurich, Switzerland., Zinzani PL; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia 'Seràgnoli,' Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy., Grever MR; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH.
Source: Blood [Blood] 2026 Jul 02; Vol. 148 (1), pp. 31-42.
Publication Type: Journal Article; Review; Practice Guideline
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Zent+CS%22">Zent CS</searchLink>; Department of Medicine and Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Tiacci+E%22">Tiacci E</searchLink>; Institute of Hematology and Center for Hemato-Oncological Research, University of Perugia and Santa Maria Della Misericordia Hospital, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Kreitman+RJ%22">Kreitman RJ</searchLink>; Laboratory of Molecular Biology, Centers for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Tadmor+T%22">Tadmor T</searchLink>; Hematology Unit, Bnai Zion Medical Center and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Tallman+MS%22">Tallman MS</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Wörmann+B%22">Wörmann B</searchLink>; Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Andritsos+LA%22">Andritsos LA</searchLink>; University of New Mexico Comprehensive Cancer Center, Albuquerque, NM.<br /><searchLink fieldCode="AU" term="%22Arons+E%22">Arons E</searchLink>; Laboratory of Molecular Biology, Centers for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Banerji+V%22">Banerji V</searchLink>; Paul Albrechtsen Research Institute and Department of Medical Oncology & Hematology, CancerCare Manitoba, and Department of Internal Medicine, Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.<br /><searchLink fieldCode="AU" term="%22Barrientos+JC%22">Barrientos JC</searchLink>; Mount Sinai Comprehensive Cancer Center, Miami Beach, FL.<br /><searchLink fieldCode="AU" term="%22Bhat+SA%22">Bhat SA</searchLink>; Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH.<br /><searchLink fieldCode="AU" term="%22Blachly+JS%22">Blachly JS</searchLink>; 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Royal Marsden NHS Foundation Trust, Sutton, United Kingdom.; UK Institute of Cancer Research, Sutton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fagarasanu+A%22">Fagarasanu A</searchLink>; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Falini+B%22">Falini B</searchLink>; Institute of Hematology and Center for Hemato-Oncological Research, University of Perugia and Santa Maria Della Misericordia Hospital, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Forconi+F%22">Forconi F</searchLink>; Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.; Haematology Department, Cancer Care Directorate, University Hospital Southampton NHS Trust, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gerrie+AS%22">Gerrie AS</searchLink>; BC Cancer Centre for Lymphoid Cancer, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Gladstone+DE%22">Gladstone DE</searchLink>; 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Lund University Cancer Center, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Kipps+TJ%22">Kipps TJ</searchLink>; Department of Medicine, Moores Cancer Center, University of California, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Lauria+F%22">Lauria F</searchLink>; University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Lozanski+G%22">Lozanski G</searchLink>; Department of Pathology, The Ohio State University Medical School, Columbus, OH.<br /><searchLink fieldCode="AU" term="%22Parikh+SA%22">Parikh SA</searchLink>; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN.<br /><searchLink fieldCode="AU" term="%22Park+JH%22">Park JH</searchLink>; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY.<br /><searchLink fieldCode="AU" term="%22Polliack+A%22">Polliack A</searchLink>; Hadassah Hebrew University Medical Center, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Quest+G%22">Quest G</searchLink>; 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Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH.
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