Brain-derived neurotrophic factor coordinates neuron-intrinsic programs to enhance axonal regeneration in human motor neurons.
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| Title: | Brain-derived neurotrophic factor coordinates neuron-intrinsic programs to enhance axonal regeneration in human motor neurons. |
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| Authors: | Vargas JNS; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UK Dementia Research Institute, University College London, London NW1 3BT, UK., Brown AL; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Sun K; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UK Dementia Research Institute, University College London, London NW1 3BT, UK., Hagemann C; Department of Basic and Clinical Neuroscience, King's College London, London SE5 9RT, UK.; UK Dementia Research Institute, King's College London, London NW1 3BT, UK.; Francis Crick Institute, London NW1 1AT, UK., Geary B; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH Scotland, UK., Villarroel-Campos D; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UK Dementia Research Institute, University College London, London NW1 3BT, UK., Bryce-Smith S; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Zanovello M; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Lombardo M; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Majewski S; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; Francis Crick Institute, London NW1 1AT, UK., Tosolini A; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Secrier M; Department of Genetics, Evolution, and Environment, UCL Genetics Institute, University College London, London WC1E 6BT, UK., Keuss MJ; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Serio A; Department of Basic and Clinical Neuroscience, King's College London, London SE5 9RT, UK.; UK Dementia Research Institute, King's College London, London NW1 3BT, UK.; Francis Crick Institute, London NW1 1AT, UK., Sleigh JN; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UK Dementia Research Institute, University College London, London NW1 3BT, UK., Fratta P; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK., Schiavo G; Department of Neuromuscular Diseases and UCL Queen Square Motor Neuron Disease Centre, UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK.; UK Dementia Research Institute, University College London, London NW1 3BT, UK. |
| Source: | Science signaling [Sci Signal] 2026 Apr 14; Vol. 19 (933), pp. eadx6752. Date of Electronic Publication: 2026 Apr 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1937-9145 |
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| DOI: | 10.1126/scisignal.adx6752 |
