The food additive 4-hexylresorcinol impairs intestinal stem cell function and exacerbates inflammatory bowel disease in Drosophila melanogaster via suppression of mapk signaling pathway.
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| Title: | The food additive 4-hexylresorcinol impairs intestinal stem cell function and exacerbates inflammatory bowel disease in Drosophila melanogaster via suppression of mapk signaling pathway. |
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| Authors: | Fan X; West China Centre of Excellence for Pancreatitis and Laboratory of Metabolism and Aging, Frontiers Science Center for Disease-Related Molecular Network and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.; Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Yan J; Department of General Internal Medicine, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, Cancer Hospital Affiliated to University of Electronic Science and Technology of China, Chengdu, Sichuan, China., Yuan Y; West China Centre of Excellence for Pancreatitis and Laboratory of Metabolism and Aging, Frontiers Science Center for Disease-Related Molecular Network and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China., Chen Y; Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China. toddychan@163.com., Chen H; West China Centre of Excellence for Pancreatitis and Laboratory of Metabolism and Aging, Frontiers Science Center for Disease-Related Molecular Network and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China. chenhy82@scu.edu.cn. |
| Source: | Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Apr 14; Vol. 83 (1). Date of Electronic Publication: 2026 Apr 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41981324 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The food additive 4-hexylresorcinol impairs intestinal stem cell function and exacerbates inflammatory bowel disease in Drosophila melanogaster via suppression of mapk signaling pathway. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Fan+X%22">Fan X</searchLink>; West China Centre of Excellence for Pancreatitis and Laboratory of Metabolism and Aging, Frontiers Science Center for Disease-Related Molecular Network and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.; Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Yan+J%22">Yan J</searchLink>; Department of General Internal Medicine, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, Cancer Hospital Affiliated to University of Electronic Science and Technology of China, Chengdu, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Yuan+Y%22">Yuan Y</searchLink>; West China Centre of Excellence for Pancreatitis and Laboratory of Metabolism and Aging, Frontiers Science Center for Disease-Related Molecular Network and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China. toddychan@163.com.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; West China Centre of Excellence for Pancreatitis and Laboratory of Metabolism and Aging, Frontiers Science Center for Disease-Related Molecular Network and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China. chenhy82@scu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229705402%22">Cellular and molecular life sciences : CMLS</searchLink> [Cell Mol Life Sci] 2026 Apr 14; Vol. 83 (1). <i>Date of Electronic Publication: </i>2026 Apr 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9705402 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-9071 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221420682X%22">1420682X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Life Sci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41981324 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00018-026-06159-4 Languages: – Code: eng Text: English Titles: – TitleFull: The food additive 4-hexylresorcinol impairs intestinal stem cell function and exacerbates inflammatory bowel disease in Drosophila melanogaster via suppression of mapk signaling pathway. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fan X – PersonEntity: Name: NameFull: Yan J – PersonEntity: Name: NameFull: Yuan Y – PersonEntity: Name: NameFull: Chen Y – PersonEntity: Name: NameFull: Chen H IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 04 Text: 2026 Apr 14 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1420-9071 Numbering: – Type: volume Value: 83 – Type: issue Value: 1 Titles: – TitleFull: Cellular and molecular life sciences : CMLS Type: main |
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