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Promoting APC function of B cells via reprogramming the fatty acid metabolism enhances anticancer immunity in metastatic ovarian cancer.

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Title: Promoting APC function of B cells via reprogramming the fatty acid metabolism enhances anticancer immunity in metastatic ovarian cancer.
Authors: Zhang H; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Yu C; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Du W; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Li H; Department of Gynecology and Obstetrics, Tianjin Key Laboratory of Female Reproductive Health and Eugenics, Tianjin Medical University General Hospital, Tianjin, 300052, China., Liu Z; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Li X; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Yue Y; Inner Mongolia Cancer Center, Peking University Cancer Hospital (Inner Mongolia Campus)/Affiliated Cancer Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region, Hohhot, 010000, China., Wang B; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Wang H; School of Basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, China., Ouyang Y; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Wu H; Department of Pathology, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, 300100, China., Feng X; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Yu J; Central Laboratory, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China., Liu Y; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Ji B; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Cai S; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Zhang H; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China., Deng W; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China. dengweimin@tmu.edu.cn.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Apr 15; Vol. 75 (5). Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Promoting APC function of B cells via reprogramming the fatty acid metabolism enhances anticancer immunity in metastatic ovarian cancer.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Yu+C%22">Yu C</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Du+W%22">Du W</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Gynecology and Obstetrics, Tianjin Key Laboratory of Female Reproductive Health and Eugenics, Tianjin Medical University General Hospital, Tianjin, 300052, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Yue+Y%22">Yue Y</searchLink>; Inner Mongolia Cancer Center, Peking University Cancer Hospital (Inner Mongolia Campus)/Affiliated Cancer Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region, Hohhot, 010000, China.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; School of Basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Ouyang+Y%22">Ouyang Y</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Wu+H%22">Wu H</searchLink>; Department of Pathology, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, 300100, China.<br /><searchLink fieldCode="AU" term="%22Feng+X%22">Feng X</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Central Laboratory, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Ji+B%22">Ji B</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Cai+S%22">Cai S</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China.<br /><searchLink fieldCode="AU" term="%22Deng+W%22">Deng W</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Diseases and Microenvironment of Ministry of Education of China, Tianjin Institute of Immunology, Tianjin Medical University, No.22 Qixiangtai Road, Heping District, Tianjin, 300070, China. dengweimin@tmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%228605732%22">Cancer immunology, immunotherapy : CII</searchLink> [Cancer Immunol Immunother] 2026 Apr 15; Vol. 75 (5). <i>Date of Electronic Publication: </i>2026 Apr 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8605732 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203407004%22">03407004 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Immunother <i>Subsets: </i>MEDLINE
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