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Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl-tRNA Synthetase Boosts Genetic Code Expansion in E. coli.

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Title: Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl-tRNA Synthetase Boosts Genetic Code Expansion in E. coli.
Authors: Koch NG; Bioanalytics Group, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.; Biocatalysis Group, Institute of Chemistry, Technische Universität Berlin, Berlin, Germany.; Department of Chemistry, Institute of Physical Chemistry, University of Basel, Basel, Switzerland.; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Goettig P; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University, Salzburg, Austria., Nash MA; Department of Chemistry, Institute of Physical Chemistry, University of Basel, Basel, Switzerland.; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Rappsilber J; Bioanalytics Group, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, Scotland, UK., Budisa N; Biocatalysis Group, Institute of Chemistry, Technische Universität Berlin, Berlin, Germany.; Chemical Synthetic Biology Group, Department of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada.
Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Jul; Vol. 13 (38), pp. e13600. Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl-tRNA Synthetase Boosts Genetic Code Expansion in E. coli.
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  Data: <searchLink fieldCode="AU" term="%22Koch+NG%22">Koch NG</searchLink>; Bioanalytics Group, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.; Biocatalysis Group, Institute of Chemistry, Technische Universität Berlin, Berlin, Germany.; Department of Chemistry, Institute of Physical Chemistry, University of Basel, Basel, Switzerland.; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Goettig+P%22">Goettig P</searchLink>; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Paracelsus Medical University, Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Nash+MA%22">Nash MA</searchLink>; Department of Chemistry, Institute of Physical Chemistry, University of Basel, Basel, Switzerland.; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rappsilber+J%22">Rappsilber J</searchLink>; Bioanalytics Group, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, Scotland, UK.<br /><searchLink fieldCode="AU" term="%22Budisa+N%22">Budisa N</searchLink>; Biocatalysis Group, Institute of Chemistry, Technische Universität Berlin, Berlin, Germany.; Chemical Synthetic Biology Group, Department of Chemistry, University of Manitoba, Winnipeg, Manitoba, Canada.
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              Text: 2026 Jul
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