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Adding induction intrathecal cytarabine in newly diagnosed CNS2 B-acute lymphoblastic leukemia does not improve outcomes.

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Title: Adding induction intrathecal cytarabine in newly diagnosed CNS2 B-acute lymphoblastic leukemia does not improve outcomes.
Authors: Lee-Miller CA; Division of Pediatric Hematology, Oncology, Transplant and Cellular Therapy, Department of Pediatrics, University of Wisconsin, Madison, WI., Kairalla JA; Department of Biostatistics, Colleges of Medicine, Public Health and Health Professions, University of Florida, Gainesville, FL., Hibbitts E; Department of Biostatistics, Colleges of Medicine, Public Health and Health Professions, University of Florida, Gainesville, FL., Winick NJ; Division of Pediatric Hematology/Oncology, Department of Pediatrics, Simmons Cancer Center, UT Southwestern, Dallas, TX., Rabin KR; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California San Francisco, San Francisco, CA., Angiolillo A; Servier Pharmaceuticals, Boston, MA., Schore RJ; Cancer and Blood Disorders Center, Department of Pediatrics, Children's National Hospital, Washington DC., Salzer WL; Department of Pediatrics, Uniformed Services University, Bethesda, MD., Burke MJ; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI., Loh ML; Ben Towne Center for Childhood Cancer and Blood Disorder Research, Department of Pediatrics, Seattle Children's Hospital and the Fred Hutch Cancer Center, University of Washington, Seattle, WA., Raetz EA; Division of Pediatric Hematology/Oncology, Department of Pediatrics, New York University Langone Health, New York, NY., Hunger SP; Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Devidas M; Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN., Teachey DT; Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA., Gupta S; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada., McNeer JL; Division of Pediatric Hematology/Oncology, The University of Utah, Primary Children's Hospital, Salt Lake City, UT.
Source: Blood advances [Blood Adv] 2026 Jun 23; Vol. 10 (12), pp. 4184-4192.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
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  Data: Adding induction intrathecal cytarabine in newly diagnosed CNS2 B-acute lymphoblastic leukemia does not improve outcomes.
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  Data: <searchLink fieldCode="AU" term="%22Lee-Miller+CA%22">Lee-Miller CA</searchLink>; Division of Pediatric Hematology, Oncology, Transplant and Cellular Therapy, Department of Pediatrics, University of Wisconsin, Madison, WI.<br /><searchLink fieldCode="AU" term="%22Kairalla+JA%22">Kairalla JA</searchLink>; Department of Biostatistics, Colleges of Medicine, Public Health and Health Professions, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Hibbitts+E%22">Hibbitts E</searchLink>; Department of Biostatistics, Colleges of Medicine, Public Health and Health Professions, University of Florida, Gainesville, FL.<br /><searchLink fieldCode="AU" term="%22Winick+NJ%22">Winick NJ</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, Simmons Cancer Center, UT Southwestern, Dallas, TX.<br /><searchLink fieldCode="AU" term="%22Rabin+KR%22">Rabin KR</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Angiolillo+A%22">Angiolillo A</searchLink>; Servier Pharmaceuticals, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Schore+RJ%22">Schore RJ</searchLink>; Cancer and Blood Disorders Center, Department of Pediatrics, Children's National Hospital, Washington DC.<br /><searchLink fieldCode="AU" term="%22Salzer+WL%22">Salzer WL</searchLink>; Department of Pediatrics, Uniformed Services University, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Burke+MJ%22">Burke MJ</searchLink>; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.<br /><searchLink fieldCode="AU" term="%22Loh+ML%22">Loh ML</searchLink>; Ben Towne Center for Childhood Cancer and Blood Disorder Research, Department of Pediatrics, Seattle Children's Hospital and the Fred Hutch Cancer Center, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Raetz+EA%22">Raetz EA</searchLink>; Division of Pediatric Hematology/Oncology, Department of Pediatrics, New York University Langone Health, New York, NY.<br /><searchLink fieldCode="AU" term="%22Hunger+SP%22">Hunger SP</searchLink>; Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Devidas+M%22">Devidas M</searchLink>; Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN.<br /><searchLink fieldCode="AU" term="%22Teachey+DT%22">Teachey DT</searchLink>; Division of Oncology and the Center for Childhood Cancer Research, Department of Pediatrics, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22McNeer+JL%22">McNeer JL</searchLink>; Division of Pediatric Hematology/Oncology, The University of Utah, Primary Children's Hospital, Salt Lake City, UT.
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              Text: 2026 Jun 23
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