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Dual-engram architecture within a single striatal cell type distinctly controls alcohol relapse and extinction.

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Title: Dual-engram architecture within a single striatal cell type distinctly controls alcohol relapse and extinction.
Authors: Xie X; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Huang Y; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA., Chen R; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Huang Z; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Gangal H; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA., Li Z; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA., Lu J; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Cruz AM; Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX 77843, USA., Chaiprasert A; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Yu E; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Hernandez N; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Vierkant V; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Wang R; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Wang X; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA., Smith RJ; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA; Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX 77843, USA., Wang J; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA. Electronic address: jwang188@tamu.edu.
Source: Neuron [Neuron] 2026 Jun 17; Vol. 114 (12), pp. 2148-2164.e6. Date of Electronic Publication: 2026 Apr 14.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual-engram architecture within a single striatal cell type distinctly controls alcohol relapse and extinction.
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  Data: <searchLink fieldCode="AU" term="%22Xie+X%22">Xie X</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Z%22">Huang Z</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Gangal+H%22">Gangal H</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Cruz+AM%22">Cruz AM</searchLink>; Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX 77843, USA.<br /><searchLink fieldCode="AU" term="%22Chaiprasert+A%22">Chaiprasert A</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Yu+E%22">Yu E</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez+N%22">Hernandez N</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Vierkant+V%22">Vierkant V</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA.<br /><searchLink fieldCode="AU" term="%22Smith+RJ%22">Smith RJ</searchLink>; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA; Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX 77843, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Neuroscience and Experimental Therapeutics, Naresh K. Vashisht College of Medicine, Texas A&M University Health Science Center, Bryan, TX 77807, USA; Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA. Electronic address: jwang188@tamu.edu.
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  Data: <searchLink fieldCode="JN" term="%228809320%22">Neuron</searchLink> [Neuron] 2026 Jun 17; Vol. 114 (12), pp. 2148-2164.e6. <i>Date of Electronic Publication: </i>2026 Apr 14.
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        Value: 10.1016/j.neuron.2026.03.023
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              Text: 2026 Jun 17
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