The weight-loss-independent hepatoprotective benefits of semaglutide are orchestrated by intrahepatic sinusoidal endothelial GLP-1 receptors. - Gonzalez-Rellan MJ; Riobello C; Fang S; Martins da Silva E; Koehler JA; Shang R; Hammoud R; Cao X; Varela-Rey M; Drucker DJ (Cell metabolism, 2026)