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Advancing nonclinical blood pressure assessment: Current practices and future directions in drug development.

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Title: Advancing nonclinical blood pressure assessment: Current practices and future directions in drug development.
Authors: Pugsley MK; Cytokinetics, Toxicology & Safety Pharmacology, South San Francisco, CA, USA., Bhatt S; Pfizer, Safety Sciences, Drug Safety Research and Development, Groton, CT, USA., Gottfridsson C; AstraZeneca, Cardiovascular Safety Center of Excellence, CMO, Patient Safety, Oncology R&D, Gothenburg, Sweden., Hoffmann P; Independent, Beaufort, SC, USA., Koshman YE; AbbVie, Safety Pharmacology, North Chicago, IL, USA., Norton K; Charles River Laboratories, Safety Pharmacology, Senneville, Quebec, Canada., O'Brien CE; Health and Environmental Sciences Institute, Washington, DC, USA., Pierson J; Health and Environmental Sciences Institute, Washington, DC, USA. Electronic address: jpierson@hesiglobal.org., Rossman EI; GSK, Safety Pharmacology, Collegeville, PA, 19426, USA., Taraboletti A; Health and Environmental Sciences Institute, Washington, DC, USA., Zabka TS; Genentech, Development Sciences-Safety Assessment, San Francisco, CA, USA., Foley CM; AbbVie, Safety Pharmacology, North Chicago, IL, USA.
Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2026 Aug; Vol. 169, pp. 106098. Date of Electronic Publication: 2026 Apr 14.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Pugsley+MK%22">Pugsley MK</searchLink>; Cytokinetics, Toxicology & Safety Pharmacology, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bhatt+S%22">Bhatt S</searchLink>; Pfizer, Safety Sciences, Drug Safety Research and Development, Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Gottfridsson+C%22">Gottfridsson C</searchLink>; AstraZeneca, Cardiovascular Safety Center of Excellence, CMO, Patient Safety, Oncology R&D, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Hoffmann+P%22">Hoffmann P</searchLink>; Independent, Beaufort, SC, USA.<br /><searchLink fieldCode="AU" term="%22Koshman+YE%22">Koshman YE</searchLink>; AbbVie, Safety Pharmacology, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Norton+K%22">Norton K</searchLink>; Charles River Laboratories, Safety Pharmacology, Senneville, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22O'Brien+CE%22">O'Brien CE</searchLink>; Health and Environmental Sciences Institute, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Pierson+J%22">Pierson J</searchLink>; Health and Environmental Sciences Institute, Washington, DC, USA. Electronic address: jpierson@hesiglobal.org.<br /><searchLink fieldCode="AU" term="%22Rossman+EI%22">Rossman EI</searchLink>; GSK, Safety Pharmacology, Collegeville, PA, 19426, USA.<br /><searchLink fieldCode="AU" term="%22Taraboletti+A%22">Taraboletti A</searchLink>; Health and Environmental Sciences Institute, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Zabka+TS%22">Zabka TS</searchLink>; Genentech, Development Sciences-Safety Assessment, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Foley+CM%22">Foley CM</searchLink>; AbbVie, Safety Pharmacology, North Chicago, IL, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8214983 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-0295 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202732300%22">02732300 </searchLink><i>NLM ISO Abbreviation: </i>Regul Toxicol Pharmacol <i>Subsets: </i>MEDLINE
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