Topical eye treatment with JGRi1, a protein/protein interaction inhibitor, mitigates retinal degeneration.
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| Title: | Topical eye treatment with JGRi1, a protein/protein interaction inhibitor, mitigates retinal degeneration. |
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| Authors: | Cimino M; EBRI Rita Levi-Montalcini Foundation, Rome, Italy., Serkiz J; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Konstantopoulos JK; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Tisi A; Department of Science and Biomedical Technology, University of L'Aquila, L'Aquila, Italy., Cappelletti P; Department of Neurorehabilitation Sciences, Casa Cura Igea, Milan, Italy., Maccarrone R; Department of Science and Biomedical Technology, University of L'Aquila, L'Aquila, Italy., Sappington RM; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Feligioni M; EBRI Rita Levi-Montalcini Foundation, Rome, Italy. m.feligioni@ebri.it.; Department of Neurorehabilitation Sciences, Casa Cura Igea, Milan, Italy. m.feligioni@ebri.it. |
| Source: | Cell death & disease [Cell Death Dis] 2026 Apr 15; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-026-08717-x |
