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Ser423-phosphorylated MECP2 (MECP2-pS423) accumulates in human brain, cerebrospinal fluid and serum in sporadic Alzheimer's disease.

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Title: Ser423-phosphorylated MECP2 (MECP2-pS423) accumulates in human brain, cerebrospinal fluid and serum in sporadic Alzheimer's disease.
Authors: Liu QR; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA. qingrong.liu@nih.gov., Zhu M; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., Perez K; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., Yao Q; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., Horowitz MS; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., Chen Q; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., Fantoni G; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., An Y; Laboratory of Behavioral Neuroscience, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., Resnick SM; Laboratory of Behavioral Neuroscience, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., Sedlock A; Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, NIH, 9000 Rockville Pike, Bethesda, MD, 20892, USA., Maric D; Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, NIH, 9000 Rockville Pike, Bethesda, MD, 20892, USA., Serrano GE; Laboratory of Neuropathology, Banner Sun Health Research Institute, 10515 W Santa Fe Dr, Sun City, AZ, 85351, USA., Egan JM; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA., Ramsden CE; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA. chris.ramsden@nih.gov.
Source: Acta neuropathologica [Acta Neuropathol] 2026 Apr 15; Vol. 151 (1). Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ser423-phosphorylated MECP2 (MECP2-pS423) accumulates in human brain, cerebrospinal fluid and serum in sporadic Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Liu+QR%22">Liu QR</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA. qingrong.liu@nih.gov.<br /><searchLink fieldCode="AU" term="%22Zhu+M%22">Zhu M</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22Perez+K%22">Perez K</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22Yao+Q%22">Yao Q</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22Horowitz+MS%22">Horowitz MS</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22Fantoni+G%22">Fantoni G</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22An+Y%22">An Y</searchLink>; Laboratory of Behavioral Neuroscience, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22Resnick+SM%22">Resnick SM</searchLink>; Laboratory of Behavioral Neuroscience, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22Sedlock+A%22">Sedlock A</searchLink>; Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, NIH, 9000 Rockville Pike, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Maric+D%22">Maric D</searchLink>; Flow and Imaging Cytometry Core Facility, National Institute of Neurological Disorders and Stroke, NIH, 9000 Rockville Pike, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Serrano+GE%22">Serrano GE</searchLink>; Laboratory of Neuropathology, Banner Sun Health Research Institute, 10515 W Santa Fe Dr, Sun City, AZ, 85351, USA.<br /><searchLink fieldCode="AU" term="%22Egan+JM%22">Egan JM</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA.<br /><searchLink fieldCode="AU" term="%22Ramsden+CE%22">Ramsden CE</searchLink>; Laboratory of Clinical Investigation, National Institute On Aging, National Institutes of Health, 251 Bayview Blvd, Baltimore, MD, 21224, USA. chris.ramsden@nih.gov.
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              Text: 2026 Apr 15
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