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Genome-wide tandem repeat expansions modify schizophrenia risk in the presence of a 22q11.2 deletion.

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Title: Genome-wide tandem repeat expansions modify schizophrenia risk in the presence of a 22q11.2 deletion.
Authors: Cheng M; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada., Yin Y; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada., Engchuan W; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada., Heung T; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; The Dalglish Family 22q Clinic for Adults with 22q11.2 Deletion Syndrome, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada., Morrow BE; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.; Departments of Obstetrics and Gynecology and Pediatrics, Albert Einstein College of Medicine, Bronx, NY, USA., Bassett AS; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. anne.bassett@utoronto.ca.; The Dalglish Family 22q Clinic for Adults with 22q11.2 Deletion Syndrome, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada. anne.bassett@utoronto.ca.; Department of Psychiatry, University of Toronto, Toronto General Hospital Research Institute, and Campbell Family Mental Health Research Institute, Toronto, Ontario, Canada. anne.bassett@utoronto.ca., Yuen RKC; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. ryan.yuen@sickkids.ca.; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. ryan.yuen@sickkids.ca.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada. ryan.yuen@sickkids.ca.
Corporate Authors: International 22q11.2 Brain Behavior Consortium (IBBC)
Source: Molecular psychiatry [Mol Psychiatry] 2026 Apr 15. Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: Genome-wide tandem repeat expansions modify schizophrenia risk in the presence of a 22q11.2 deletion.
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  Data: <searchLink fieldCode="AU" term="%22Cheng+M%22">Cheng M</searchLink>; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Yin+Y%22">Yin Y</searchLink>; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Engchuan+W%22">Engchuan W</searchLink>; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Heung+T%22">Heung T</searchLink>; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; The Dalglish Family 22q Clinic for Adults with 22q11.2 Deletion Syndrome, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Morrow+BE%22">Morrow BE</searchLink>; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.; Departments of Obstetrics and Gynecology and Pediatrics, Albert Einstein College of Medicine, Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bassett+AS%22">Bassett AS</searchLink>; Clinical Genetics Research Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. anne.bassett@utoronto.ca.; The Dalglish Family 22q Clinic for Adults with 22q11.2 Deletion Syndrome, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada. anne.bassett@utoronto.ca.; Department of Psychiatry, University of Toronto, Toronto General Hospital Research Institute, and Campbell Family Mental Health Research Institute, Toronto, Ontario, Canada. anne.bassett@utoronto.ca.<br /><searchLink fieldCode="AU" term="%22Yuen+RKC%22">Yuen RKC</searchLink>; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. ryan.yuen@sickkids.ca.; Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. ryan.yuen@sickkids.ca.; The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, Ontario, Canada. ryan.yuen@sickkids.ca.
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