Orai1 Facilitates Angiogenesis After Myocardial Infarction Through Notch1 Signaling Pathway.

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Title: Orai1 Facilitates Angiogenesis After Myocardial Infarction Through Notch1 Signaling Pathway.
Authors: Galeano-Otero I; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.).; Reprogramming Tumor Activity and Associated Microenvironment, Bordeaux Institute of Oncology-UMR1312 Inserm, Université of Bordeaux, Pessac, France (I.G.-O., G.S., A.-M.K.)., Dominguez-Liste B; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.)., Asprón C; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.)., Fernández-Chacón M; Faculty of Health Sciences, Loyola Biomedical Research Group, Department of Health and Biomedical Sciences, Universidad Loyola Andalucía, Seville, Spain (M.F.-C.)., Escacena-Izquierdo L; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.)., Del Toro R; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.)., Rojas-Torres M; Biomedicine, Biotechnology and Public Health Department, University of Cadiz, Spain (M.R.-T., M.C.D.-R.).; Biomedical Research and Innovation Institute of Cadiz, Spain (M.R.-T., M.C.D.-R.)., Durán-Ruiz MC; Biomedicine, Biotechnology and Public Health Department, University of Cadiz, Spain (M.R.-T., M.C.D.-R.).; Biomedical Research and Innovation Institute of Cadiz, Spain (M.R.-T., M.C.D.-R.)., Siegfried G; Reprogramming Tumor Activity and Associated Microenvironment, Bordeaux Institute of Oncology-UMR1312 Inserm, Université of Bordeaux, Pessac, France (I.G.-O., G.S., A.-M.K.)., Ordóñez-Fernández A; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.)., Khatib AM; Reprogramming Tumor Activity and Associated Microenvironment, Bordeaux Institute of Oncology-UMR1312 Inserm, Université of Bordeaux, Pessac, France (I.G.-O., G.S., A.-M.K.)., Rosado JA; Department of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, Caceres, Spain (J.A.R.)., Smani T; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.).
Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2026 Jun; Vol. 46 (6), pp. e324231. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE
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  Data: Orai1 Facilitates Angiogenesis After Myocardial Infarction Through Notch1 Signaling Pathway.
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  Data: <searchLink fieldCode="AU" term="%22Galeano-Otero+I%22">Galeano-Otero I</searchLink>; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.).; Reprogramming Tumor Activity and Associated Microenvironment, Bordeaux Institute of Oncology-UMR1312 Inserm, Université of Bordeaux, Pessac, France (I.G.-O., G.S., A.-M.K.).<br /><searchLink fieldCode="AU" term="%22Dominguez-Liste+B%22">Dominguez-Liste B</searchLink>; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.).<br /><searchLink fieldCode="AU" term="%22Asprón+C%22">Asprón C</searchLink>; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.).<br /><searchLink fieldCode="AU" term="%22Fernández-Chacón+M%22">Fernández-Chacón M</searchLink>; Faculty of Health Sciences, Loyola Biomedical Research Group, Department of Health and Biomedical Sciences, Universidad Loyola Andalucía, Seville, Spain (M.F.-C.).<br /><searchLink fieldCode="AU" term="%22Escacena-Izquierdo+L%22">Escacena-Izquierdo L</searchLink>; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.).<br /><searchLink fieldCode="AU" term="%22Del+Toro+R%22">Del Toro R</searchLink>; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.).<br /><searchLink fieldCode="AU" term="%22Rojas-Torres+M%22">Rojas-Torres M</searchLink>; Biomedicine, Biotechnology and Public Health Department, University of Cadiz, Spain (M.R.-T., M.C.D.-R.).; Biomedical Research and Innovation Institute of Cadiz, Spain (M.R.-T., M.C.D.-R.).<br /><searchLink fieldCode="AU" term="%22Durán-Ruiz+MC%22">Durán-Ruiz MC</searchLink>; Biomedicine, Biotechnology and Public Health Department, University of Cadiz, Spain (M.R.-T., M.C.D.-R.).; Biomedical Research and Innovation Institute of Cadiz, Spain (M.R.-T., M.C.D.-R.).<br /><searchLink fieldCode="AU" term="%22Siegfried+G%22">Siegfried G</searchLink>; Reprogramming Tumor Activity and Associated Microenvironment, Bordeaux Institute of Oncology-UMR1312 Inserm, Université of Bordeaux, Pessac, France (I.G.-O., G.S., A.-M.K.).<br /><searchLink fieldCode="AU" term="%22Ordóñez-Fernández+A%22">Ordóñez-Fernández A</searchLink>; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).<br /><searchLink fieldCode="AU" term="%22Khatib+AM%22">Khatib AM</searchLink>; Reprogramming Tumor Activity and Associated Microenvironment, Bordeaux Institute of Oncology-UMR1312 Inserm, Université of Bordeaux, Pessac, France (I.G.-O., G.S., A.-M.K.).<br /><searchLink fieldCode="AU" term="%22Rosado+JA%22">Rosado JA</searchLink>; Department of Physiology, Institute of Molecular Pathology Biomarkers, University of Extremadura, Caceres, Spain (J.A.R.).<br /><searchLink fieldCode="AU" term="%22Smani+T%22">Smani T</searchLink>; Group of Cardiovascular Pathophysiology, Institute of Biomedicine of Seville, University Hospital of Virgen del Rocio/University of Seville/CSIC, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., A.O.-F., T.S.).; Faculty of Medicine, Department of Medical Physiology and Biophysics, University of Seville, Spain (I.G.-O., B.D.-L., C.A., L.E.-I., R.D.T., T.S.).
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