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Gender differences in non-motor symptoms in Parkinson's disease: a multicenter longitudinal study.

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Title: Gender differences in non-motor symptoms in Parkinson's disease: a multicenter longitudinal study.
Authors: Cuoco S; Department of Medicine, Surgery and Dentistry Scuola Medica Salernitana, Neuroscience Section, University of Salerno, Via Allende, 84081, Salerno, Baronissi, Italy., Russo M; Department of Chemical, Material and Industrial Production Engineering, University of Naples FEDERICO II, Naples, Italy., Picillo M; Department of Medicine, Surgery and Dentistry Scuola Medica Salernitana, Neuroscience Section, University of Salerno, Via Allende, 84081, Salerno, Baronissi, Italy., Ricciardi C; Department of Electrical Engineering and Information Technology, University of Naples FEDERICO II, Naples, Italy., Russillo MC; SC Neurologia E Stroke Unit, Ospedale Santa Croce Moncalieri, Turin, Italy., Amboni M; Department of Medicine, Surgery and Dentistry Scuola Medica Salernitana, Neuroscience Section, University of Salerno, Via Allende, 84081, Salerno, Baronissi, Italy., Arabia G; Department of Medical and Surgical Sciences, Institute of Neurology, Magna Græcia University, Catanzaro, Italy., Avanzino L; Department of Experimental Medicine (DIMES), Section of Human Physiology, University of Genoa, Genoa, Italy.; IRCCS Azienda Ospedale Metropolitana, Genoa, Italy., Canesi M; Neurorehabilitation Unit, Parkinson's Disease and Movement Disorders Center, Moriggia-Pelascini Hospital, Gravedona Ed Uniti, Como, Italy., Catania A; Medical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico 'C. Besta', Milan, Italy., Ceravolo R; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Cicero CE; Neurologic Unit, AOU 'Policlinico-San Marco', Department of Medical, Surgical Sciences and Advanced Technologies, GF Ingrassia, University of Catania, Catania, Italy., Cilia R; Department of Clinical Neurosciences, Parkinson and Movement Disorders Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Colangelo I; Medical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico 'C. Besta', Milan, Italy., Dati G; Department of Medicine, Surgery and Dentistry Scuola Medica Salernitana, Neuroscience Section, University of Salerno, Via Allende, 84081, Salerno, Baronissi, Italy., De Micco R; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli', Naples, Italy., De Rosa A; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy., Di Fonzo A; IRCCS Ca' Granda Ospedale Maggiore Policlinico, Neurology Unit, Milan, Italy., Eleopra R; Department of Clinical Neurosciences, Parkinson and Movement Disorders Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Fetoni V; UOS Neurologia P.O. Fatebenefratelli-ASST Fatebenefratelli-Sacco, Milan, Italy., Garavaglia B; Medical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico 'C. Besta', Milan, Italy., Giglio A; Department of Neurosciences and Reproductive and Odontostomatological Sciences, Federico II University, Naples, Italy., Giuntini M; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Invernizzi F; Medical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico 'C. Besta', Milan, Italy., Lazzeri G; Centro Parkinson E Parkinsonismi, Milan, Italy., Marchese R; IRCCS Azienda Ospedale Metropolitana, Genoa, Italy., Nicoletti A; Neurologic Unit, AOU 'Policlinico-San Marco', Department of Medical, Surgical Sciences and Advanced Technologies, GF Ingrassia, University of Catania, Catania, Italy., Pacchetti C; Parkinson's Disease and Movement Disorders Unit, IRCCS Mondino Foundation, Pavia, Italy., Panteghini C; Medical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico 'C. Besta', Milan, Italy., Pilleri M; Centro Parkinson E Parkinsonismi, Milan, Italy., Radicati FG; IRCCS San Raffaele, Rome, Italy., Reale C; Medical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico 'C. Besta', Milan, Italy., Scaglione C; IRCCS Istituto Delle Scienze Neurologiche Di Bologna, Bologna, Italy., Soricelli A; IRCCS SYNLAB SDN, Naples, Italy., Stocchi F; IRCCS San Raffaele, Rome, Italy.; University San Raffaele, Rome, Italy., Tessitore A; Department of Advanced Medical and Surgical Sciences, University of Campania 'Luigi Vanvitelli', Naples, Italy., Vacca L; IRCCS San Raffaele, Rome, Italy., Volontè MA; IRCCS San Raffaele Scientific Institute, Neurology Unit, Milan, Italy., Volpi G; SSD Malattie Endocrine Diabetologia, ASST Fatebenefratelli-Sacco, Milan, Italy., Zangaglia R; Parkinson's Disease and Movement Disorders Unit, IRCCS Mondino Foundation, Pavia, Italy., Amato F; Department of Electrical Engineering and Information Technology, University of Naples FEDERICO II, Naples, Italy., Barone P; Department of Medicine, Surgery and Dentistry Scuola Medica Salernitana, Neuroscience Section, University of Salerno, Via Allende, 84081, Salerno, Baronissi, Italy.; IRCCS SYNLAB SDN, Naples, Italy., Pellecchia MT; Department of Medicine, Surgery and Dentistry Scuola Medica Salernitana, Neuroscience Section, University of Salerno, Via Allende, 84081, Salerno, Baronissi, Italy. mpellecchia@unisa.it.; IRCCS SYNLAB SDN, Naples, Italy. mpellecchia@unisa.it.
Corporate Authors: SIN Gender Neurology Study Group
Source: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2026 Apr 16; Vol. 47 (5). Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100959175 Publication Model: Electronic Cited Medium: Internet ISSN: 1590-3478 (Electronic) Linking ISSN: 15901874 NLM ISO Abbreviation: Neurol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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