Efficacy of bepotastine compared with hydroxyzine in preventing rituximab-induced infusion-related reactions in non-hodgkin lymphoma patients: a phase II, double-blind, multicenter, and randomized trial.
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| Title: | Efficacy of bepotastine compared with hydroxyzine in preventing rituximab-induced infusion-related reactions in non-hodgkin lymphoma patients: a phase II, double-blind, multicenter, and randomized trial. |
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| Authors: | Kitahiro Y; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. ykitahi@med.kobe-u.ac.jp., Minami H; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Yamamoto K; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.; Department of Integrated Clinical and Basic Pharmaceutical Sciences, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan., Yakushijin K; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Kurata K; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Sakai R; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Saeki M; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Okazoe-Hirakawa Y; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Iida K; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Murase N; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Harima I; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan., Kitamura N; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan., Itohara K; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan., Omura T; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan., Sugimoto T; Department of Hematology and Oncology, Kita-Harima Medical Center, Ono, Japan., Takakura H; Department of Hematology and Oncology, Kita-Harima Medical Center, Ono, Japan., Kitao A; Department of Hematology and Oncology, Kita-Harima Medical Center, Ono, Japan., Takahashi M; Department of Pharmacy, Kita-Harima Medical Center, Ono, Japan., Shimoyama M; Department of Hematology and Oncology, Kohnan Medical Center, Kobe, Japan., Okuno M; Department of Pharmacy, Kohnan Medical Center, Kobe, Japan., Yano I; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. |
| Source: | International journal of clinical oncology [Int J Clin Oncol] 2026 Jun; Vol. 31 (6), pp. 979-988. Date of Electronic Publication: 2026 Apr 16. |
| Publication Type: | Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study |
| Journal Info: | Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 9616295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7772 (Electronic) Linking ISSN: 13419625 NLM ISO Abbreviation: Int J Clin Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41989666 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Efficacy of bepotastine compared with hydroxyzine in preventing rituximab-induced infusion-related reactions in non-hodgkin lymphoma patients: a phase II, double-blind, multicenter, and randomized trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kitahiro+Y%22">Kitahiro Y</searchLink>; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. ykitahi@med.kobe-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Minami+H%22">Minami H</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+K%22">Yamamoto K</searchLink>; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.; Department of Integrated Clinical and Basic Pharmaceutical Sciences, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.<br /><searchLink fieldCode="AU" term="%22Yakushijin+K%22">Yakushijin K</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Kurata+K%22">Kurata K</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Sakai+R%22">Sakai R</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Saeki+M%22">Saeki M</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Okazoe-Hirakawa+Y%22">Okazoe-Hirakawa Y</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Iida+K%22">Iida K</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Murase+N%22">Murase N</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Harima+I%22">Harima I</searchLink>; Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Hospital and Graduate School of Medicine, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Kitamura+N%22">Kitamura N</searchLink>; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.<br /><searchLink fieldCode="AU" term="%22Itohara+K%22">Itohara K</searchLink>; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.<br /><searchLink fieldCode="AU" term="%22Omura+T%22">Omura T</searchLink>; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.<br /><searchLink fieldCode="AU" term="%22Sugimoto+T%22">Sugimoto T</searchLink>; Department of Hematology and Oncology, Kita-Harima Medical Center, Ono, Japan.<br /><searchLink fieldCode="AU" term="%22Takakura+H%22">Takakura H</searchLink>; Department of Hematology and Oncology, Kita-Harima Medical Center, Ono, Japan.<br /><searchLink fieldCode="AU" term="%22Kitao+A%22">Kitao A</searchLink>; Department of Hematology and Oncology, Kita-Harima Medical Center, Ono, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+M%22">Takahashi M</searchLink>; Department of Pharmacy, Kita-Harima Medical Center, Ono, Japan.<br /><searchLink fieldCode="AU" term="%22Shimoyama+M%22">Shimoyama M</searchLink>; Department of Hematology and Oncology, Kohnan Medical Center, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Okuno+M%22">Okuno M</searchLink>; Department of Pharmacy, Kohnan Medical Center, Kobe, Japan.<br /><searchLink fieldCode="AU" term="%22Yano+I%22">Yano I</searchLink>; Department of Pharmacy, Kobe University Hospital, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229616295%22">International journal of clinical oncology</searchLink> [Int J Clin Oncol] 2026 Jun; Vol. 31 (6), pp. 979-988. <i>Date of Electronic Publication: </i>2026 Apr 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Tokyo%22">Springer-Verlag Tokyo </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>9616295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1437-7772 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213419625%22">13419625 </searchLink><i>NLM ISO Abbreviation: </i>Int J Clin Oncol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41989666 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10147-026-03012-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 979 Titles: – TitleFull: Efficacy of bepotastine compared with hydroxyzine in preventing rituximab-induced infusion-related reactions in non-hodgkin lymphoma patients: a phase II, double-blind, multicenter, and randomized trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kitahiro Y – PersonEntity: Name: NameFull: Minami H – PersonEntity: Name: NameFull: Yamamoto K – PersonEntity: Name: NameFull: Yakushijin K – PersonEntity: Name: NameFull: Kurata K – PersonEntity: Name: NameFull: Sakai R – PersonEntity: Name: NameFull: Saeki M – PersonEntity: Name: NameFull: Okazoe-Hirakawa Y – PersonEntity: Name: NameFull: Iida K – PersonEntity: Name: NameFull: Murase N – PersonEntity: Name: NameFull: Harima I – PersonEntity: Name: NameFull: Kitamura N – PersonEntity: Name: NameFull: Itohara K – PersonEntity: Name: NameFull: Omura T – PersonEntity: Name: NameFull: Sugimoto T – PersonEntity: Name: NameFull: Takakura H – PersonEntity: Name: NameFull: Kitao A – PersonEntity: Name: NameFull: Takahashi M – PersonEntity: Name: NameFull: Shimoyama M – PersonEntity: Name: NameFull: Okuno M – PersonEntity: Name: NameFull: Yano I IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1437-7772 Numbering: – Type: volume Value: 31 – Type: issue Value: 6 Titles: – TitleFull: International journal of clinical oncology Type: main |
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