Anti-arthritic efficacy of geraniol and methotrexate via miRNA-driven NLRP3 inflammasome suppression in rat adjuvant-induced arthritis.

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Title: Anti-arthritic efficacy of geraniol and methotrexate via miRNA-driven NLRP3 inflammasome suppression in rat adjuvant-induced arthritis.
Authors: Gowayed MA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University in Alexandria, Canal El Mahmoudia Street, Beside Green Plaza Complex, Alexandria, 21648, Egypt., Hassan SA; Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., Kamel MA; Department of Biochemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt., Helmy MW; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt., El-Ganainy SO; Department of Pharmacology, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, Abu Kir Campus, Alexandria, 1029, Egypt. samarossama@hotmail.com.
Source: Inflammopharmacology [Inflammopharmacology] 2026 May; Vol. 34 (5), pp. 3347-3361. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9112626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-5608 (Electronic) Linking ISSN: 09254692 NLM ISO Abbreviation: Inflammopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1568-5608
DOI:10.1007/s10787-026-02198-2