An opposing molecular gradient axis underlies primate cortical organization.
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| Title: | An opposing molecular gradient axis underlies primate cortical organization. |
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| Authors: | Huang Z; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; BGI Research, Hangzhou, China.; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China., Yang Q; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; Lingang Laboratory, Shanghai, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, China., Li S; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; BGI Research, Hangzhou, China.; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China., Zhu X; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; State Key Laboratory of Genetic Evolution and Animal Models, National Research Facility for Phenotypic and Genetic Analysis of Model Animals (Primate Facility), National Resource Center for Non-Human Primates, Yunnan Key Laboratory of Animal Models and Human Disease Mechanisms, and KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China., Wang H; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Lin J; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; Sino-Danish College, University of Chinese Academy of Sciences, Beijing, China., Zhan Y; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Wu Y; BGI Research, Hangzhou, China., Wang Z; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Majka P; Laboratory of Neuroinformatics, Nencki Institute of Experimental Biology of the Polish Academy of Sciences, Warsaw, Poland., Qu H; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Atapour N; Neuroscience Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Clayton, VIC, Australia., Yang T; BGI Research, Hangzhou, China., Lin Y; BGI Research, Hangzhou, China.; Key Laboratory of Brain Cell Mapping of Zhejiang Province, BGI Research, Hangzhou, China., Cui L; BGI Research, Hangzhou, China., Yao YG; State Key Laboratory of Genetic Evolution and Animal Models, National Research Facility for Phenotypic and Genetic Analysis of Model Animals (Primate Facility), National Resource Center for Non-Human Primates, Yunnan Key Laboratory of Animal Models and Human Disease Mechanisms, and KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.; Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China., Liang Z; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Liu Z; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China., Li C; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Wei W; Lingang Laboratory, Shanghai, China., Zhou Y; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Ma S; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Shen Z; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China., Wei X; BGI Research, Hangzhou, China., Xu X; BGI Research, Hangzhou, China.; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China., Liu S; BGI Research, Hangzhou, China.; Key Laboratory of Brain Cell Mapping of Zhejiang Province, BGI Research, Hangzhou, China.; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China., Li C; Lingang Laboratory, Shanghai, China., Poo M; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China., Liu L; BGI Research, Hangzhou, China.; Key Laboratory of Brain Cell Mapping of Zhejiang Province, BGI Research, Hangzhou, China.; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China., Rosa MGP; Neuroscience Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Clayton, VIC, Australia., Sun Y; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; Shanghai Key Laboratory of Precision Gene Editing and Clinical Translation, Shanghai, China., Hao S; BGI Research, Hangzhou, China.; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.; Key Laboratory of Brain Cell Mapping of Zhejiang Province, BGI Research, Hangzhou, China.; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Hangzhou, China., Liu C; Institute of Neuroscience, State Key Laboratory of Genetic Evolution and Animal Models, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.; Sino-Danish College, University of Chinese Academy of Sciences, Beijing, China.; Shanghai Key Laboratory of Child Brain and Development, Shanghai, China. |
| Source: | Science (New York, N.Y.) [Science] 2026 Apr 16; Vol. 392 (6795), pp. eaea2673. Date of Electronic Publication: 2026 Apr 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.aea2673 |
