GRASP55 maintains lysosome function by controlling sorting of lysosomal enzymes at the Golgi.

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Title: GRASP55 maintains lysosome function by controlling sorting of lysosomal enzymes at the Golgi.
Authors: Nüchel J; Max Planck Institute for Biology of Ageing (MPI-AGE), Cologne, Germany. nuechel.julian@uni-koeln.de.; University of Cologne, Faculty of Medicine and University Hospital Cologne, Center for Biochemistry, Cologne, Germany. nuechel.julian@uni-koeln.de.; University of Cologne, Center for Molecular Medicine Cologne (CMMC), Cologne, Germany. nuechel.julian@uni-koeln.de., Omidi M; Department of Osteology and Biomechanics (IOBM), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Fernandes SA; Max Planck Institute for Biology of Ageing (MPI-AGE), Cologne, Germany., Tauber M; University of Cologne, Faculty of Medicine and University Hospital Cologne, Center for Biochemistry, Cologne, Germany., Pohl S; Department of Osteology and Biomechanics (IOBM), University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Plomann M; University of Cologne, Faculty of Medicine and University Hospital Cologne, Center for Biochemistry, Cologne, Germany., Demetriades C; Max Planck Institute for Biology of Ageing (MPI-AGE), Cologne, Germany. Demetriades@age.mpg.de.; University of Cologne, Cologne Excellence Cluster for Aging and Aging-Associated Diseases (CECAD), Cologne, Germany. Demetriades@age.mpg.de.; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen (RUG), University Medical Center Groningen (UMCG), Groningen, The Netherlands. Demetriades@age.mpg.de.
Source: EMBO reports [EMBO Rep] 2026 Jun; Vol. 27 (11), pp. 2947-2972. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-3178
DOI:10.1038/s44319-026-00773-w