Mechanistic multiphysics modeling reveals how blood pulsation drives CSF flow, pressure, and brain deformation under physiological and injection conditions.
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| Title: | Mechanistic multiphysics modeling reveals how blood pulsation drives CSF flow, pressure, and brain deformation under physiological and injection conditions. |
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| Authors: | Li Z; School of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN, 47906, USA., Feng K; School of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN, 47906, USA., Gomez H; School of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN, 47906, USA. hectorgomez@purdue.edu.; Weldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Dr, West Lafayette, IN, 47906, USA. hectorgomez@purdue.edu. |
| Source: | Fluids and barriers of the CNS [Fluids Barriers CNS] 2026 Apr 16; Vol. 23 (1). Date of Electronic Publication: 2026 Apr 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Biomed Central Country of Publication: England NLM ID: 101553157 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-8118 (Electronic) Linking ISSN: 20458118 NLM ISO Abbreviation: Fluids Barriers CNS Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2045-8118 |
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| DOI: | 10.1186/s12987-026-00804-7 |