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A versatile, positive-going voltage indicator that enables accessible two-photon recordings in vivo.

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Title: A versatile, positive-going voltage indicator that enables accessible two-photon recordings in vivo.
Authors: McDonald AJ; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Land MA; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Yang S; Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX, 77005, USA., Hakam N; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Villette V; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France., Zhu J; Department of Neuroscience, University of California, Berkeley, CA, 94720, USA., Galdamez M; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., de La Puebla MF; Kavli Institute for Systems Neuroscience, Trondheim, Norway., Lu X; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.; Systems, Synthetic, and Physical Biology Program, Rice University, Houston, TX, 77005, USA., Foran G; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Torne-Srivastava T; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Campillo B; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Liu H; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Dong X; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Lai S; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Shorey M; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Abdallah H; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Banks R; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Mamontova A; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Shan YY; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Kroeger R; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Law RG; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Hu M; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Santos DG; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France., Bradley J; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France., Lombardini A; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France.; Institut de Neurosciences de la Timone, UMR 7289, CNRS and Aix Marseille Université, 13005 Marseille, France., Mathieu B; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France., Ayon A; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France., Natan RG; Department of Neuroscience, University of California, Berkeley, CA, 94720, USA., Yuan H; Department of Physics, University of California, Berkeley, CA, 94720, USA., Reimer J; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA., Bourdieu L; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France., Ji N; Department of Neuroscience, University of California, Berkeley, CA, 94720, USA.; Department of Physics, University of California, Berkeley, CA, 94720, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Zong W; Kavli Institute for Systems Neuroscience, Trondheim, Norway., St-Pierre F; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.; Systems, Synthetic, and Physical Biology Program, Rice University, Houston, TX, 77005, USA.; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, 77030, USA.; Department of Electrical and Computer Engineering, Rice University, Houston, TX, 77005, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 10. Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: A versatile, positive-going voltage indicator that enables accessible two-photon recordings in vivo.
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  Data: <searchLink fieldCode="AU" term="%22McDonald+AJ%22">McDonald AJ</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Land+MA%22">Land MA</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX, 77005, USA.<br /><searchLink fieldCode="AU" term="%22Hakam+N%22">Hakam N</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Villette+V%22">Villette V</searchLink>; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; Department of Neuroscience, University of California, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Galdamez+M%22">Galdamez M</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22de+La+Puebla+MF%22">de La Puebla MF</searchLink>; Kavli Institute for Systems Neuroscience, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Lu+X%22">Lu X</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.; Systems, Synthetic, and Physical Biology Program, Rice University, Houston, TX, 77005, USA.<br /><searchLink fieldCode="AU" term="%22Foran+G%22">Foran G</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Torne-Srivastava+T%22">Torne-Srivastava T</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Campillo+B%22">Campillo B</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Liu+H%22">Liu H</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Dong+X%22">Dong X</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Lai+S%22">Lai S</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Shorey+M%22">Shorey M</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Abdallah+H%22">Abdallah H</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Banks+R%22">Banks R</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Mamontova+A%22">Mamontova A</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Shan+YY%22">Shan YY</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Kroeger+R%22">Kroeger R</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Law+RG%22">Law RG</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Hu+M%22">Hu M</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Santos+DG%22">Santos DG</searchLink>; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France.<br /><searchLink fieldCode="AU" term="%22Bradley+J%22">Bradley J</searchLink>; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France.<br /><searchLink fieldCode="AU" term="%22Lombardini+A%22">Lombardini A</searchLink>; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France.; Institut de Neurosciences de la Timone, UMR 7289, CNRS and Aix Marseille Université, 13005 Marseille, France.<br /><searchLink fieldCode="AU" term="%22Mathieu+B%22">Mathieu B</searchLink>; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France.<br /><searchLink fieldCode="AU" term="%22Ayon+A%22">Ayon A</searchLink>; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France.<br /><searchLink fieldCode="AU" term="%22Natan+RG%22">Natan RG</searchLink>; Department of Neuroscience, University of California, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Yuan+H%22">Yuan H</searchLink>; Department of Physics, University of California, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Reimer+J%22">Reimer J</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Bourdieu+L%22">Bourdieu L</searchLink>; Institut de Biologie de l'École Normale Supérieure (IBENS), École Normale Supérieure, CNRS, INSERM, Université PSL, Paris F-75005, France.<br /><searchLink fieldCode="AU" term="%22Ji+N%22">Ji N</searchLink>; Department of Neuroscience, University of California, Berkeley, CA, 94720, USA.; Department of Physics, University of California, Berkeley, CA, 94720, USA.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.<br /><searchLink fieldCode="AU" term="%22Zong+W%22">Zong W</searchLink>; Kavli Institute for Systems Neuroscience, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22St-Pierre+F%22">St-Pierre F</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, TX, 77030, USA.; Systems, Synthetic, and Physical Biology Program, Rice University, Houston, TX, 77005, USA.; Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, 77030, USA.; Department of Electrical and Computer Engineering, Rice University, Houston, TX, 77005, USA.
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