Transcriptional and spatial profiling of fibroblasts from human lungs highlights CTHRC1+ cells as fibrogenic signaling hubs in fibrosis.
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| Title: | Transcriptional and spatial profiling of fibroblasts from human lungs highlights CTHRC1+ cells as fibrogenic signaling hubs in fibrosis. |
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| Authors: | Vanegas-Avendano ND; Division of Pulmonary, Critical Care, & Sleep Medicine, Department of Internal Medicine, The Ohio State University, Wexner Medical Center, Columbus, OH, USA., Chen H; Division of Pulmonary, Critical Care, & Sleep Medicine, Department of Internal Medicine, The Ohio State University, Wexner Medical Center, Columbus, OH, USA.; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Wellmerling J; Department of Physiology & Biomedical Engineering. Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA., Rodriguez-Lopez J; Division of Pulmonary, Critical Care, & Sleep Medicine, Department of Internal Medicine, The Ohio State University, Wexner Medical Center, Columbus, OH, USA., Ghobashi A; Division of Pulmonary, Critical Care, & Sleep Medicine, Department of Internal Medicine, The Ohio State University, Wexner Medical Center, Columbus, OH, USA.; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Peters V; Division of Pulmonary, Critical Care, & Sleep Medicine, Department of Internal Medicine, The Ohio State University, Wexner Medical Center, Columbus, OH, USA., Sen C; Children's Discovery and Innovation Institute, Broad StemCell Research Center, Jonsson Comprehensive Cancer Center, Departments of Pediatrics and Pulmonary Medicine, University of California, Los Angeles, California, USA., Reader BF; Human Tissue Biorepository. OSU Wexner Medical Center Comprehensive Transplant Center, The Ohio State University, Columbus, OH, USA., Shilo K; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Gomperts B; Children's Discovery and Innovation Institute, Broad StemCell Research Center, Jonsson Comprehensive Cancer Center, Departments of Pediatrics and Pulmonary Medicine, University of California, Los Angeles, California, USA., Ma Q; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH, USA.; Pelotonia Institute for Immuno-Oncology, The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA., Mora AL; Division of Pulmonary, Critical Care, & Sleep Medicine, Department of Internal Medicine, The Ohio State University, Wexner Medical Center, Columbus, OH, USA., Tschumperlin DJ; Department of Physiology & Biomedical Engineering. Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA., Rojas M; Division of Pulmonary, Critical Care, & Sleep Medicine, Department of Internal Medicine, The Ohio State University, Wexner Medical Center, Columbus, OH, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 10. Date of Electronic Publication: 2026 Apr 10. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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