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Demethoxycurcumin exhibits amoebicidal activity against Acanthamoeba triangularis trophozoites and cysts and inhibits encystation.

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Title: Demethoxycurcumin exhibits amoebicidal activity against Acanthamoeba triangularis trophozoites and cysts and inhibits encystation.
Authors: Boonhok R; Department of Medical Technology, School of Allied Health Sciences, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand., Senghoi W; Department of Medical Technology, School of Allied Health Sciences, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand., Tedasen A; Department of Medical Technology, School of Allied Health Sciences, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand., Sangkanu S; School of Allied Health Sciences, Southeast Asia Water Team (SEA Water Team) and World Union for Herbal Drug Discovery (WUHeDD), Walailak University, Nakhon Si Thammarat, 80160, Thailand., Lim CL; Division of Applied Biomedical Science and Biotechnology, School of Health Sciences, International Medical University, Kuala Lumpur, 57000, Malaysia., Pereira ML; CICECO-Aveiro Institute of Materials and Department of Medical Sciences, University of Aveiro, Aveiro, 3810-193, Portugal., Rahmatullah M; Department of Biotechnology and Genetic Engineering, University of Development Alternative, Lalmatia, Dhaka, 1209, Bangladesh., Wilairatana P; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Rachathewee, Bangkok, 10400, Thailand., Wiart C; The Institute for Tropical Biology and Conservation, University of Malaysia Sabah, Jalan UMS, Kota Kinabalu, Sabah, 88400, Malaysia., Dolma KG; Department of Microbiology, Sikkim Manipal Institute of Medical Sciences (SMIMS), Sikkim, 737102, India., Paul AK; School of Pharmacy and Pharmacology, University of Tasmania, Hobart, Tasmania, 7001, Australia., Gupta M; Department of Pharmaceutics, Delhi Pharmaceutical Sciences and Research University, New Delhi, 110017, India., Rahman MA; Department of Biochemistry and Molecular Biology, University of Chittagong, Chittagong, 4331, Bangladesh., Bunluepuech K; Department of Medical Technology, School of Allied Health Sciences, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand., Sundara S; Department of Biotechnology, AVIT Chennai Campus, Vinayaka Mission's Research Foundation (VMRF), Paiyanoor, Tamil Nadu, 603104, India., Mahboob T; Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, 56000, Malaysia., Nissapatorn V; Futuristic Science Research Center-School of Science, World Union for Herbal Drug Discovery (WUHeDD), and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Source: Current research in parasitology & vector-borne diseases [Curr Res Parasitol Vector Borne Dis] 2026 Feb 16; Vol. 9, pp. 100362. Date of Electronic Publication: 2026 Feb 16 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918226380706676 Publication Model: eCollection Cited Medium: Internet ISSN: 2667-114X (Electronic) Linking ISSN: 2667114X NLM ISO Abbreviation: Curr Res Parasitol Vector Borne Dis Subsets: PubMed not MEDLINE
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  Data: Demethoxycurcumin exhibits amoebicidal activity against Acanthamoeba triangularis trophozoites and cysts and inhibits encystation.
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  Data: <searchLink fieldCode="AU" term="%22Boonhok+R%22">Boonhok R</searchLink>; Department of Medical Technology, School of Allied Health Sciences, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand.<br /><searchLink fieldCode="AU" term="%22Senghoi+W%22">Senghoi W</searchLink>; Department of Medical Technology, School of Allied Health Sciences, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand.<br /><searchLink fieldCode="AU" term="%22Tedasen+A%22">Tedasen A</searchLink>; Department of Medical Technology, School of Allied Health Sciences, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand.<br /><searchLink fieldCode="AU" term="%22Sangkanu+S%22">Sangkanu S</searchLink>; School of Allied Health Sciences, Southeast Asia Water Team (SEA Water Team) and World Union for Herbal Drug Discovery (WUHeDD), Walailak University, Nakhon Si Thammarat, 80160, Thailand.<br /><searchLink fieldCode="AU" term="%22Lim+CL%22">Lim CL</searchLink>; Division of Applied Biomedical Science and Biotechnology, School of Health Sciences, International Medical University, Kuala Lumpur, 57000, Malaysia.<br /><searchLink fieldCode="AU" term="%22Pereira+ML%22">Pereira ML</searchLink>; CICECO-Aveiro Institute of Materials and Department of Medical Sciences, University of Aveiro, Aveiro, 3810-193, Portugal.<br /><searchLink fieldCode="AU" term="%22Rahmatullah+M%22">Rahmatullah M</searchLink>; Department of Biotechnology and Genetic Engineering, University of Development Alternative, Lalmatia, Dhaka, 1209, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Wilairatana+P%22">Wilairatana P</searchLink>; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Rachathewee, Bangkok, 10400, Thailand.<br /><searchLink fieldCode="AU" term="%22Wiart+C%22">Wiart C</searchLink>; The Institute for Tropical Biology and Conservation, University of Malaysia Sabah, Jalan UMS, Kota Kinabalu, Sabah, 88400, Malaysia.<br /><searchLink fieldCode="AU" term="%22Dolma+KG%22">Dolma KG</searchLink>; Department of Microbiology, Sikkim Manipal Institute of Medical Sciences (SMIMS), Sikkim, 737102, India.<br /><searchLink fieldCode="AU" term="%22Paul+AK%22">Paul AK</searchLink>; School of Pharmacy and Pharmacology, University of Tasmania, Hobart, Tasmania, 7001, Australia.<br /><searchLink fieldCode="AU" term="%22Gupta+M%22">Gupta M</searchLink>; Department of Pharmaceutics, Delhi Pharmaceutical Sciences and Research University, New Delhi, 110017, India.<br /><searchLink fieldCode="AU" term="%22Rahman+MA%22">Rahman MA</searchLink>; Department of Biochemistry and Molecular Biology, University of Chittagong, Chittagong, 4331, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Bunluepuech+K%22">Bunluepuech K</searchLink>; Department of Medical Technology, School of Allied Health Sciences, and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand.<br /><searchLink fieldCode="AU" term="%22Sundara+S%22">Sundara S</searchLink>; Department of Biotechnology, AVIT Chennai Campus, Vinayaka Mission's Research Foundation (VMRF), Paiyanoor, Tamil Nadu, 603104, India.<br /><searchLink fieldCode="AU" term="%22Mahboob+T%22">Mahboob T</searchLink>; Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, 56000, Malaysia.<br /><searchLink fieldCode="AU" term="%22Nissapatorn+V%22">Nissapatorn V</searchLink>; Futuristic Science Research Center-School of Science, World Union for Herbal Drug Discovery (WUHeDD), and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, 80160, Thailand.
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  Data: <searchLink fieldCode="JN" term="%229918226380706676%22">Current research in parasitology & vector-borne diseases</searchLink> [Curr Res Parasitol Vector Borne Dis] 2026 Feb 16; Vol. 9, pp. 100362. <i>Date of Electronic Publication: </i>2026 Feb 16 (<i>Print Publication: </i>2026).
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