Single nuclei/cell transcriptomics reveal DMD driven cell dynamics and mechanisms of fibroblast inflammatory tissue priming in human dystrophic muscle.
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| Title: | Single nuclei/cell transcriptomics reveal DMD driven cell dynamics and mechanisms of fibroblast inflammatory tissue priming in human dystrophic muscle. |
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| Authors: | Chesmore KN; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Barthélémy F; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences, University of California, Los Angeles, Los Angeles, CA, USA., Rengarajan S; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Scripture-Adams DD; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences, University of California, Los Angeles, Los Angeles, CA, USA., Sen A; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Nasif D; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Little I; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences, University of California, Los Angeles, Los Angeles, CA, USA., Wang RT; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Nieves-Rodriguez S; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Corona RI; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Institute for Precision Health, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Steady N; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences, University of California, Los Angeles, Los Angeles, CA, USA., Yip A; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences, University of California, Los Angeles, Los Angeles, CA, USA., Douine ED; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Nelson SF; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Institute for Precision Health, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Miceli MC; Center for Duchenne Muscular Dystrophy at UCLA, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences, University of California, Los Angeles, Los Angeles, CA, USA. |
| Source: | Research square [Res Sq] 2026 Apr 08. Date of Electronic Publication: 2026 Apr 08. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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